Program 912,
  October 17, 2005

 

A. New Genetic Analysis Shakes Up Salamanders' Family Tree

Narrator: This is Science Today. A new, genetic analysis of the largest family of salamanders has pretty much shaken their family tree. Rachel Mueller, a graduate student of Integrative Biology at the University of California, Berkeley, says the Plethodontid salamanders, a lungless group that breathes through their skin, make up two-thirds of the world’s known species of salamanders.

Mueller: They’ve been studied quite a bit and all the studies about them have assumed that we knew sort of the four major groups of Plethodontids salamanders. So, not only who was in each group, but also how those groups were related to each other. And those relationships were based primarily on bone data – so we thought we’d just double check that bone data with genetic data.

Narrator: Mueller sequenced genetic data of these salamanders at the UC-operated Joint Genome Institute, which played a big part in helping decode the human genome.

Mueller: We ended up finding that actually three out of the four groups weren’t actually groups at all. So, it definitely is a hint that in many cases, we’re underestimating greatly the biodiversity in species where we haven’t looked at them genetically just because they look very similar to one another.

Narrator: For Science Today, I’m Larissa Branin.

B. The Conflicting Data about Virtual Colonoscopy


Narrator: This is Science Today. Colon cancer is the second leading cause of cancer death in the United States. There are several screening options available – colonoscopy being the gold standard test, but over the years, virtual colonoscopy – a less invasive procedure – has gained in popularity.

Ladabaum: Virtual colonoscopy has been in development for the last several years. Most recently, there have been some technical advances that have suggested that this test may actually be quite good at detecting colorectal cancers and polyps, but the published data have been conflicting.

Narrator: Dr. Uri Ladabaum of the University of California, San Francisco recently conducted a national study using data from conflicting studies of the two colonoscopy procedures and concluded that virtual colonoscopy is not ready for widespread use.

Ladabaum: The initial studies that were very promising tended to be in patients who had a high rate of polyps and cancer and often, tests look better when you have a population that is enriched with pathology. So what many of us were waiting for were studies in a general population at average risk.

Narrator: For Science Today, I’m Larissa Branin.

C. Adolescent Obesity: An Issue of Energy Intake & Expenditure

Narrator: This is Science Today. Childhood and adolescent obesity has been increasing dramatically over the last generation and a lack of vigorous activity is a primary factor in this trend. Dr. Kevin Patrick, a professor of family and preventive medicine at the University of California, San Diego’s School of Medicine, says adolescent obesity is an issue of energy intake and energy expenditure.

Patrick: With respect to the expenditure of energy, the two clusters of considerations relate to how active kids are and how sedentary they are.

Narrator: From a research standpoint, Patrick says the understanding of activity and sedentary behaviors differ.

Patrick: Physical activity is a really different behavioral construct than a sedentary behavior and when we think about working with kids and families and settings from the school to the communities to clinical settings, we have to recognize that there really are different sorts of approaches that have to be taken, but they’re all part of this big equation of energy balance and that’s really the important thing that seems to have gone awry, over the last twenty years or so.

Narrator: For Science Today, I’m Larissa Branin.

D. The Largest Ethanol-Powered Fleet in California

Narrator: This is Science Today. Ethanol is an alternative fuel produced from agricultural bio-mass products such as corn or soybean and it’s being used to power 60 vehicles at the University of California-managed Lawrence Berkeley National Laboratory. Dan Prestella, the Lab’s fleet operations supervisor, says this makes their onsite motor pool the largest ethanol-powered fleet in the Golden State.

Prestella: This station has been about three years in the making. We put in for a grant through the DOE in early 2002 and we were able to get enough funds to do this and we identified ethanol as our product of choice to meet our alternative fuel vehicle requirements.

Narrator: Prestella explains that an executive order asked all federal agencies to make sure that 75% of their replacement vehicles use alternative fuel to reduce air emissions.

Prestella: We have this above ground, four thousand gallon ethanol tank and what it does is it feeds one of our new pumps. A customer drives up to the pump in an ethanol powered vehicle, inserts a key into a card reader, punches in the mileage and then they pump just as you would at a normal gas station.

Narrator: For Science Today, I’m Larissa Branin.

E. Better Think Twice Before You Skip Breakfast

Narrator: This is Science Today. Have you ever thought that skipping breakfast would be an easy way to cut back calories? Well, a nationwide study out of the University of California, Berkeley, has found that skipping breakfast is actually bad for keeping off weight. Nutritional epidemiologist, Gladys Block, explains.

Block: People might think that if they skip breakfast that they're doing themselves a favor, and in fact they're not. And in fact it was interesting because the people who skip breakfast actually had lower total energy, total calorie intake, and yet they had much higher body mass index.

Narrator: Block says that skipping breakfast represents disordered eating habits associated with weight gain and that the nature of what you have for breakfast also makes a big difference.

Block: The people who had eggs and bacon for breakfast were the highest body weight actually, whereas people who had breakfast cereal for breakfast were among the lowest. So maybe the actual nature of your breakfast makes a difference in addition to eating it at all.

Narrator: For Science Today, I'm Larissa Branin.



 

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