Program 866,
  November 30, 2004

 

A. A Proposed FAA Regulation May Do More Harm than Good

Narrator: This is Science Today. A proposed Federal Aviation Administration regulation that would require child restraint seats on commercial airlines for children under the age of two would likely cause more deaths than it prevents. Thomas Newman, a professor of epidemiology and biostatistics at the University of California, San Francisco, says that's because parents may choose to drive instead of fly.

Newman: The concern is if parents have to pay for a ticket, depending on how much the ticket costs and how long the trip is, they might choose to drive rather than fly.

Narrator: Per mile, driving is riskier than flying, so Newman says the regulation could cause more deaths from road traffic accidents than it prevents from airplane crashes.

Newman: We estimated that the risk per mile traveled of these families with small children was only thirty percent of the national average of risk per mile traveled. But still, even taking that into account, if more than about five to ten percent of those chose to drive rather than fly, then the deaths on the road exceed those prevented.

Narrator: For Science Today, I'm Larissa Branin.

B. A 'BubbleCam' Provides New Insight into Ocean Processes

Narrator: This is Science Today. When waves break in the open ocean, they create millions of bubbles, which play an important role in a variety of ocean and atmospheric processes. At the University of California, San Diego's Scripps Institution of Oceanography, researchers have developed a high-tech 'BubbleCam', which oceanographer Grant Deane says is providing new insight into the characteristics of bubbles.

Deane: Understanding the origin of the bubbles and the numbers and sizes that are produced and the physics of that process is important for modelists, who are trying to model this very fundamental process.

Narrator: The BubbleCam is a high-tech video camera with a powerful lens and focusing system, which enables oceanographers to take finely sliced pictures as waves break.

Deane: We think we've discovered the mechanism controlling the bubble production in the ocean waves.

Narrator: These results may someday be used to develop instruments that can remotely monitor greenhouse gas transfer. For Science Today, I'm Larissa Branin.

C. How Our Early Ancestors Endured Chronic Stress

Narrator: This is Science Today. For people living in a society that induces chronic stress, it's not uncommon to turn to high-fat comfort foods and put on abdominal weight. University of California, San Francisco physiology professor, Mary Dallman, says from the standpoint of evolution, modest weight gain when you're chronically stressed can be helpful.

Dallman: It's smart as can be because in a chronic stress situation-for instance, a drought or a famine- it's a very neat pool of fat because it sits very close to liver, and when it's mobilized, its energy can be used by the liver to make more glucose.

Narrator: But as Dallman notes, there's not much worry about famine in today's fast-food culture.

Dallman: Convenience food is all over the place-every block you walk to has the availability and low price of food that is really high fat or high carbohydrate and this can become habitual and that's what is a big problem.

Narrator: For Science Today, I'm Larissa Branin.

D. Putting Tobacco Waste to Good Use

Narrator: This is Science Today. It may seem highly unlikely, but Bruce Lipshutz, a biochemist at the University of California, Santa Barbara, has found a way to put tobacco waste to good use. Lipshutz is synthesizing an invaluable vitamin supplement, called Coenzyme Q10, or CoQ, using a compound derived from tobacco waste.

Lipshutz: Well what we've identified are starting materials that we feel are readily available. So for example the key component that will make synthesis possible is a product of tobacco waste called solanesol.

Narrator: Lipshutz says using this raw material, solanesol, to produce CoQ is a cheaper and more efficient method than the fermentation method currently used in Japan.

Lipshutz: People literally have this waste from processing tobacco, especially in many foreign countries, like India, China, and to some degree in the United States. And they just throw it out; they use it as fertilizer.

Narrator: For Science Today, I'm Larissa Branin.

E. New Insight into a Lethal Cancer

Narrator: This is Science Today. Pancreatic cancer is usually diagnosed late, so the median survival is in the range of four months after diagnosis, so not only is it incurable, it is also very rapid. That's why researchers like Matthias Hebrok of the University of California, San Francisco, are studying the development and growth of this lethal malignancy.

Hebrok: The prognosis is probably one of the worst that you can get. So for us to understand what makes the tumor grow and what molecules it depends on for full growth and survival potentially increases our arsenal of weapons we can throw at this cancer and hopefully combat it.

Narrator: Hebrok helped discover a link between a cell signaling pathway present during embryonic development and pancreatic cancer and that the pathway could be blocked by a molecule isolated by plants called cyclopamine.

Hebrok: So by just adding cyclopamine to those pancreatic cancer cell lines, we could ask the question if the inhibition of the pathway changes the fate of those cells.

Narrator: For Science Today, I'm Larissa Branin.

 

 

 

 

 

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu