Program 826,
  February 24, 2004

 

A. Two Factors Found to be Associated with Breast Cancer Recurrence

Narrator: This is Science Today. Women treated with lumpectomy alone for a non-invasive form of breast cancer known as ductal carcinoma in situ, or DCIS, were more likely to have a recurrence of the disease if their lesion was of a high nuclear grade or if it was a palpable lesion detected during a clinical exam. Karla Kerlikowske of the University of California, San Francisco's Veterans Affairs Medical Center, led the six-year study.

Kerlikowske: I think it can change management in the sense that those that have low nuclear grade or even intermediate nuclear grade, lumpectomy alone is probably sufficient therapy, along with surveillance and monitoring. But if you have high nuclear grade, I would more strongly consider getting adjuvant radiation or maybe taking tamoxifen. So, our goal is to try and treat DCIS less aggressively than in the past and based on some sort of risk factor and knowledge of the disease, as opposed to just aggressively treating everybody as if all these lesions are going to go on and be invasive cancer.

Narrator: For Science Today, I'm Larissa Branin

B. How to Prevent the Risk of Food-Related Choking in Young Children

Narrator: This is Science Today. According to human health experts, every five days a child in the United States dies from choking on food. University of California, Berkeley nutrition expert Joanne Ikeda, says infants and children up to three years of age are most susceptible.

Ikeda: The food that is most often the culprit is hot dog products. Unfortunately, they're round and they're fairly bulky and it's easy for them to be caught in the trachea, so it's very important that hot dog products be cut in smaller pieces, not in round, circular pieces for children. Those circular pieces should then be cut in half or in quarters.

Narrator: Other foods that children choke on are round candies - especially of the hard variety. The more nutritious, yet equally circular, grapes and nuts may also cause a child to choke.

Ikeda: So those are the foods that babysitters and parents need to be very, very careful about giving to children under three years old.

Narrator: For Science Today, I'm Larissa Branin.

C. A Colorectal Test that's Inadequate in Elderly Female Patients

Narrator: This is Science Today. When it comes to detecting colorectal cancer, flexible sigmoidoscopy is one of the most common screening tools. But a University of California, San Francisco study found that the chance of an inadequate sigmoidoscopy examination increases with old age. In fact, Louise Walter, a staff physician in geriatrics at the Veterans Affairs Medical Center, discovered that women were twice as likely as men to have inadequate sigmoidoscopies.

Walter: The most likely explanation is probably anatomical differences - women's colons are different than men's. There's a sharper turn at the sigmoid colon, making the flexible sigmoidoscopy harder to get around.

Narrator: There are three screening tools for colorectal cancer - the colonoscopy, the flexible sigmoidoscopy and the fecal occult blood test. Walter says there are risks and benefits to each.

Walter: This study is certainly not meant to say you shouldn't get screened. It's more trying to - of the three screening tests that you could do, which one would be the most likely to have more benefits than risks and this is just helping in that decision.

Narrator: For Science Today, I'm Larissa Branin.

D. Understanding Common Vision Problems

Narrator: This is Science Today. About half of the world population is either nearsighted or farsighted. Another great percentage has astigmatism and everyone past the age of 45 will develop age-related loss of vision. Ophthalmologists at the University of California, Irvine are striving to get to the root of why these vision problems occur. Dr. Peter McDonnell says this includes trying to understand what it is about aging that causes a loss in the ability to read.

McDonnell: And our belief is by understanding actually why these happen, we can best target and create treatment to prevent them or to treat these problems. With patients who have trouble reading, we'll often to a procedure called monovision, where we correct one eye for distance vision and leave the other eye purposely somewhat nearsighted to allow the patient to read with that eye.

Narrator: This has proven very successful …

McDonnell: Eighty percent of people tolerate monovision very successfully and find that it most improves their lives in terms of minimizing their dependence on any corrective lenses.

Narrator: For Science Today, I'm Larissa Branin.

E. Do Happy Marriages Lead to Better Health?

Narrator: This is Science Today. It's been known for years that married people tend to live longer than those who stay unmarried. Now a study from the University of California, Berkeley shows that a happy marriage makes for a healthier old age. Cenita Kupperbusch, a doctoral candidate in psychology, says a long-term study of aging couples proves that a good marriage can be the best medicine-at least for men.

Kupperbusch: Husbands who had increases in marital satisfaction also had increases in their health. On the other hand, this was a positive relationship. So husbands who had decreases in marital satisfaction also showed decreases in health.

Narrator: The study followed 78 elderly couples over a period of thirteen years. Using surveys and observation, the researchers found a clear link between marital satisfaction and health. But Kupperbusch says that the reason for that link is not yet known.

Kupperbusch: We don't know that changes in marital satisfaction are necessarily causing changes in health but we know there is some relationship between those two. It could be that changes in health are causing changes in marital satisfaction.

Narrator: For Science Today, I'm Larissa Branin.

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu