Program 812,
  November 18, 2003

 

A. A Cell Signaling Pathway Linked to Pancreatic Cancer

Narrator: This is Science Today. A cell signaling pathway active during embryonic development has been linked to pancreatic cancer - one of the fourth leading causes of cancer deaths in this country. Matthias Hebrok of the University of California, San Francisco, says this signaling pathway is known as the Hedgehog pathway - a name derived from its spiky physical appearance.

Hebrok: The Hedgehog signaling pathway has been implicated in cancer and we had early on information that it is expressed in specific tissue that are believed to give rise to adenocarcinoma, the prevalent pancreatic cancer.

Narrator: Using human cell lines, the researchers demonstrated that pancreatic cancer growth could be halted by chemically blocking the Hedgehog pathway.

Hebrok: What I really hope for is that eventually Hedgehog inhibitors will become part of a cocktail either with already existing chemotherapeutical treatment options that are not very good for pancreatic cancer or with novel ones that will help to at least give patients hope.

Narrator: For Science Today, I'm Larissa Branin.

B. An Experimental System Boosts Cotton Crop Potentials

Narrator: This is Science Today. Agricultural scientists at the University of California are studying experimental systems that may boost cotton crop potentials. Cotton specialist Bob Hutmacher of the University of California, Davis, says for over four years now, they've been studying a double-row cotton planting concept that has led to a 4 to 12% increase in yield.

Hutmacher: What we've been looking at essentially a change in planting systems that would have two planted rows per bed. In addition, under quite a few different conditions, we find a little bit of advantage in terms of earliness of the crop, which can help in terms of getting it off the field earlier. The other thing that we've found is some potential for the plants to develop and kind of shade out potential weeds that may be coming up and that's proven to be a fairly consistent advantage with this type of system.

Narrator: California cotton production represents about 10 to 14% of the total U.S. yearly production. For Science Today, I'm Larissa Branin.

C. An Incentive to Buy a Hydrogen Fuel Cell Vehicle

Narrator: This is Science Today. Most people's largest purchase, after their home, is their car-but on average, people only use their car one hour a day. That's why Daniel Kammen of the Energy Resources Group at the University of California, Berkeley, recommends people consider buying a hydrogen fuel cell vehicle, which can earn you cash back during those other twenty-three hours.

Kammen: If you can drive your car to work, the fuel cell powered car to work, and leave it running while you're at work and sell electricity back to the grid, now you've got a neat vehicle to grid power source. And most people are at work during mid-afternoon, that's when the price of power goes up the most, because that's when the demand is highest, and that's when you are at work, but your car can be generating power. You then get in your car, drive home, and then leave the car turned on essentially and then run your home off of it.

Narrator: Kammen says taking your power source around with you works in conjunction with another progressive trend their group is working on that's called onsite generation with microgrids. For Science Today, I'm Larissa Branin.

D. The Benefits of Vitamin C Supplementation

Narrator: This is Science Today. Vitamin C supplementation offers significant protection to people exposed to secondhand tobacco smoke. Gladys Block, a professor of nutritional epidemiology at the University of California, Berkeley, found that taking 500 milligrams of vitamin C significantly reduced oxidative damage, which can lead to heart and lung disease.

Block: We know from other studies that people who are exposed to secondhand smoke have an increased risk of heart disease, an increased risk of cancer and an increased risk of various lung diseases and so on. So what we were testing was, can these vitamin supplements lower your oxidative damage? And in fact, we found that it did.

Narrator: Block says no one can get the desired 500 milligrams from diet alone.

Block: Probably fifty percent of the population on any given day gets less than about 90 milligrams. So, eat your fruits and vegetables, but I think also take a vitamin supplement as an additional boost.

Narrator: For Science Today, I'm Larissa Branin.

E. Activism Against Soil Extinction Gains Momentum

Narrator: This is Science Today. You may not have yet heard the slogan "save the dirt," but activism against soil extinction in the United States is gaining momentum. Soil specialist Ron Amundson of the University of California, Berkeley, says that as the number of extinct soil types increases, eco-friendly activists are being reminded that saving endangered species means protecting the soil that sustains them.

Amundson: There is indeed a relationship indeed between endangered plants and endangered soils in the United States. As one might expect, as certain soil types disappear, soil types that because of their properties harbor certain plant types, as those soils disappear, the plants themselves tend to disappear.

Narrator: Amundson encourages setting aside undisturbed areas where unique soils can help rare species to flourish.

Amundson: So I think among professional conservationists, there's a growing sense that it's not just what's growing there, it's the whole environment that's very important in conservation and preservation efforts.

Narrator: For Science Today, I'm Larissa Branin.

 

 

 

 

 

 

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