Program 797,
  August 5, 2003

 

A. Researchers Link Sleep Apnea to Brain Damage

Narrator: This is Science Today. Sleep apnea, which is a stoppage of breathing during sleep, has long been attributed to a narrowed airway caused by enlarged tonsils, a small jaw or obesity. But UCLA scientists have recently linked obstructive sleep apnea to brain damage in areas that regulate breathing and speech. Ronald Harper, a professor of neurobiology, led the study.

Harper: Using magnetic resonance imaging procedures, we examined the structure of the brain in various locations and found that certain areas were smaller in affected patients. Some of these areas were concerned with control of the airway muscles and control of other muscles and particular control of expression of speech.

Narrator: The researchers then serendipitously discovered that nearly forty percent of the patients in their study also stuttered from early childhood.

Harper: The evidence that a speech impediment appears to be associated, with obstructive sleep apnea suggests that perhaps the brain area's contributing to the onset of the syndrome.

Narrator: For Science Today, I'm Larissa Branin.

B. A Computer Simulation Program Successfully Used for Operation Iraqi Freedom

Narrator: This is Science Today. A complex, computer coded simulation program, originally developed by scientists at the Lawrence Livermore National Laboratory, was used to develop tactics to take tanks into downtown Baghdad during Operation Iraqi Freedom. Bob Greenwalt is deputy director of the Lab's Joint Conflict and Tactical Simulation project, or JCATS.

Greenwalt: We developed the simulation here - we don't use it, but we get a lot of feedback from our field users and we received an E-mail from the training site in Europe and they were very excited about it because apparently in January, the First Armored Division in Germany was asked to develop the tactics for moving heavy armor into a large urban place like Baghdad. And they did that and they used JCATS as the tool to try out ideas - see what worked, what didn't work and to refine their tactics.

Narrator: The scenario was then used in Kuwait to train the Third Armored Division and the Marines before the war started.

Greenwalt: That's the reason we do this kind of job here. The Lab works in support of national problems and that's a problem that we think we solved.

Narrator: For Science Today, I'm Larissa Branin.

C. What Women Should Know about Hormone Replacement Therapy (HRT)

Narrator: This is Science Today. Many women suffering from menopause are prescribed hormone replacement therapy to treat their symptoms. But recent, major studies found that hormone replacement therapies increase the risk for breast cancer, heart disease, stroke and blood clots. Joanne Ikeda, a nutritionist at the University of California, Berkeley says many women are now turning to alternative therapies, including a diet rich in phytoestrogens found in soy products.

Ikeda:There is some research to show that soy-based foods can relieve mild menopausal symptoms. However, it really won't impact if you're having major menopausal symptoms.

Narrator: Ikeda says the best bet is to speak to your doctor about hormone replacement therapy.

Ikeda: Your physician can help you - perhaps can lower the doses, change the type, but physicians are concerned, they're aware of this new research information.

Narrator: For Science Today, I'm Larissa Branin.

D. Researchers Challenge the Use of Ethanol as a Gasoline Additive

Narrator: This is Science Today. Researchers at the University of California, Berkeley, are challenging America's current position on the use of ethanol as a gasoline additive. Derived from corn, ethanol use is set to double to 5 billion gallons a year by 2012. Geoengineer Tad Patzek, who led the study, argues the costs of transporting ethanol are too high.

Patzek: The United States has a spider web of pipelines. In fact, most people don't know that we have literally thousands of hundreds of miles of pipelines. But these pipelines are not designed to transport ethanol.

Narrator: Patzek says currently most pipeline companies refuse to transport ethanol because it is highly corrosive and can damage the seals in the pipelines. So, ethanol would have to travel from the Midwest in a costly combination including barges through the Gulf of Mexico and tankers through the Panama Canal.

Patzek: And of course, transporting such huge quantities of highly flammable, dangerous fuel entails its own problems.

Narrator: For Science Today, I'm Larissa Branin.

E. A Microchip that May Accelerate the Process of Drug Discovery

Narrator: This is Science Today. There's a microchip being developed at the University of California, Berkeley that could accelerate the process of drug discovery. Mechanical engineer Yong Huang says traditionally scientists developing drugs use a test that can only tell if a toxin kills a cell, but with this new chip, scientists will be able to understand the dying process of a cell much more dynamically-and hopefully discover drugs faster.

Huang: The nice thing about our technology is that it tells you what happened with the cell membrane while cell is dying.

Narrator: This new wealth of information about the process of cell death should speed up drug discovery and toxin detection.

Huang:I believe that with this technology what we can do is study how the cells responded to different agents, drugs or toxins. And to build kind of like an information library which can also be used for drug discovery and also for toxic detection.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu