Program 796,
  July 29, 2003

 

A. A Fingerprint of Human Effects on Global Climate

Narrator: This is Science Today. By studying climate model experiments, scientists at the Lawrence Livermore National Laboratory have discovered another fingerprint of human effects on global climate. Lab scientist Ben Santer says they found that in the last two decades, increases in the height of the tropopause - a transition zone between the upper and lower atmospheres - are linked to ozone depletion and an increase in greenhouse gases.

Santer: There's still uncertainty about the global scale's sign of the change in tropospheric temperatures. Our work suggests that the troposphere may well have warmed and without that warming you couldn't really get this pronounced increase in tropopause height.

Narrator: This is the first time scientists examined whether observed changes in tropopause height corresponded with projections from climate model experiments on greenhouse warming.

Santer: If the models are even in the ballpark, then we can expect some large changes in climate over the next century and it behooves us to try and understand those changes.

Narrator: For Science Today, I'm Larissa Branin.

B. A Microchip that can Detect a Biochemical Attack

Narrator: This is Science Today. University of California, Berkeley scientists have created a microchip that can be used to sound the alarm for a biochemical attack. Yong Huang, who led the study, says this "canary on a chip" uses microelectronics to instantly detect the dying process of a cell.

Huang:The core part of our technology is a microchip that can grow cells on it and also incorporate the cell into this inanimate electrical circuit. As a result we can very precisely monitor or detect the membrane integrity, which is a hallmark of cell death.

Narrator: The idea is, the instant toxins cause a cell to die, an alarm goes off.

Huang: You can easily imagine that this kind of technology could be implemented as a universal cell based toxic detection device, which is very critical in a battle against potential biowarfare or bioterrorism.

Narrator: For Science Today, I'm Larissa Branin.

C. Mechanical Thinning of Urban Forests: A Barrier Against Wildfire

Narrator:This is Science Today. As the recent wildfires in the West proved, heavy brush and small trees surrounding homes can make a catastrophic combination. Forestry scientists are proposing that removing some of the forestland debris may save many homes. University of California Area Natural Resources advisor, Michael de Lasaux, says they've tested small equipment that can remove small trees and debris and create a defensible space near a home.

De Lasaux:The advantages of this equipment is that they're a small tractor that has the ability to accommodate various pieces of equipment. It's very small, only six feet wide, so it can negotiate in and amongst trees fairly readily without causing damage, but also around the homes without causing too much concern by the homeowner.

Narrator:Attachments on this tractor include a small mower, a cutter and a processor.

De Lasaux: After we've cut and processed the tree into logs, we bring in a grapple, the grapple has the ability to grab onto all these small logs and then carry them to a place where we'll concentrate them and determine what next to do with them.

Narrator: For Science Today, I'm Larissa Branin.

D. A Doorway to a New Form of Learning

Narrator:This is Science Today. How do people ultimately get over their fears? That's a question UCLA researchers are interested in answering. Mark Barad, a professor of psychiatry and bio-behavioral sciences, is studying a process called extinction, which refers to learning to inhibit fear under circumstances where it's not appropriate.

Barad: We believe that by targeting this extinction system, we would get rid of these excessive fears and what's nice about it is we're not erasing the ability of that person to summon up an appropriate fear response to appropriate dangers - even if it's the same kind of danger because extinction - this process, is very context specific.

Narrator: Barad helped discover one of the specific molecules involved in the process of extinction.

Barad: This is an important finding and it's like having a doorway into a new form of learning. The other thing is that now the difference means that we can now look for drugs that affect this system in particular and use those to develop a way to make extinction go faster without messing up other forms of learning.

Narrator: For Science Today, I'm Larissa Branin.

E. The Challenge of Providing a 'Morning After' Pill for HIV

Narrator: This is Science Today. AIDS researchers at the University of California, San Francisco, are studying a little-known 'morning after' drug intervention for HIV exposure, called post-exposure prophylaxis, or PEP. Dr. Michelle Roland says that anyone can start PEP within 72 hours after a potential exposure.

Roland:Any healthcare provider can provide post-exposure prophylaxis. These are medicines that are approved for the treatment of HIV disease and they are covered on all insurance formularies because they are very standard drugs.

Narrator: Roland says that although anyone can get PEP, it will be difficult to popularize the drug treatment because many doctors aren't familiar with assessing risks or treating HIV.

Roland: I think it's going to be a challenge for clinics, emergency departments, HIV clinics, STD clinics, to think about over time whether they want to provide this service because they will need to develop a group of healthcare providers who have expertise.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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