Program 784,
  May 6, 2003

 

A. New Insight into Embryonic Facial Development

Narrator: This is Science Today. The sculpting of the face during embryonic development may be more open to change than was previously thought-this according to researchers at the University of California, San Francisco. Jill Helms, a professor of orthopaedic surgery, led the study.

Helms: What we found in our study was that the length of time during which the face, its pattern can be altered, is greatly extended. In other words, defects could occur over a much wider range, but that also means that if defects did occur, and you wanted to think about strategies for repairing defects, you'd have a much bigger window of time in which to do it.

Narrator: In lab studies with chick and quail embryos, researchers found that by transplanting tissues, they could reprogram the face to adopt a new fate.

Helms: It was surprising first of all that a little piece of tissue had that much instructive capability. It meant that even when we transplanted it to a new location, the cells were still responsive to the signals. Meaning that plasticity of the face was maintained for much, much longer than we thought.

B. Agriculture's Changing Economic Landscape

Narrator: This is Science Today. Over the next few decades, the nation's agricultural community will be facing a changing economic landscape. Agricultural economist, Steven Blank, of the University of California, Davis says that's because American farmers and ranchers will be facing more global competition from places like Eastern Europe, South America, China and India.

Blank: As these other countries expand their output, that means that global supplies, the total out there is up and because we have very much a global market now for a lot of agricultural commodities, the expansion in one part of the world in terms of their output will definitely affect the prices received by American producers.

Narrator: For farmers, it means continued need for technological innovation to keep pace with all the prices. For consumers, it's good news at the register.

Blank: Obviously if there's more food being produced and it's going to be higher and higher quality and more and more variety, as purchasers and consumers of food, that's a good thing. We'll have more to choose from and it's going to cost us less.

Narrator: For Science Today, I'm Larissa Branin.

C. The First Breakthrough in Understanding SARS

Narrator: This is Science Today. The first critical breakthrough in the rush to understand severe acute respiratory syndrome, or SARS, was made possible by microarray virus screening technology pioneered at the University of California, San Francisco. Arthur Reingold, an infectious disease expert at UC Berkeley, comments on this brand new technology.

Reingold: What that technology allows you to do, is with enormous speed and power, to compare the nucleic acids from a virus or a bacterium or something else with an enormous array of known agents to see if this one is identical to, similar to, or completely different from perhaps thousands or tens of thousands of other known agents.

Narrator:: In just one day, microarray enabled scientists to determine that SARS was in the coronavirus family.

Reingold: So it's a wonderful technology that is certainly helping examine different infectious agents. And it has promise in terms of detection of those agents.

Narrator: For Science Today, I'm Larissa Branin.

D. Computer Technology's Contribution to Brain Research

Narrator: This is Science Today. For over a decade, UCLA's Laboratory of Neuro Imaging has been dedicated to improving the understanding of the human brain. It was about ten years ago that Dr. Arthur Toga, the laboratory's director, co-conceived the idea to set up a huge database that would serve as a brain atlas for researchers and physicians.

Toga: One of the great, lucky aspects of this project was the power of computers has made it possible. You know, fifteen years ago, it probably wouldn't have been possible, so the emergence of supercomputers, the ability to store all of this data, the ability to acquire data at sufficient resolution, the MRI scanners, all of these things emerged as the concept emerged.

Narrator: The result is a comprehensive, ever-evolving online atlas of the human brain.

Toga: We've already had many spin-off projects from this, doing population studies of schizophrenia, Alzheimer's Disease, autism, brain development, normal brain aging - and these have utilized the concepts that have emerged from this brain atlas project.

Narrator: For Science Today, I'm Larissa Branin.

E. The Impact of a Smoke-free Environment

Narrator: This is Science Today. In an effort to prove that public smoking bans lower heart attack rates, Dr. Stan Glantz, a professor of medicine at the University of California, San Francisco, has been studying the isolated community of Helena, Montana, where in just six months a non-smoking ordinance has slashed heart attack rates in the community. Glantz says importantly, all heart attack patients go to the same hospital - that is, the only hospital, in Helena.

Glantz: I worked with two physicians from Helena and we looked at admissions to the hospital for heart attacks. And what we found was that for people who lived in or very close to Helena, there was a 60% drop in the number of admissions for heart attacks while this non-smoking ordinance was in effect. Whereas, for people who lived further away and didn't have the benefits of the smoke-free environments, there was no change in the admissions. So creating smoke-free environments has an immediate, very positive effect on heart attacks.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu