Program 758,
  November 5, 2002

 

A. Chinese Medicine Enhances Treatment of Hepatitis B Patients

Narrator: This is Science Today. New research has found that Chinese herbal medicine, combined with standard therapy, can enhance the treatment outcomes for patients with chronic Hepatitis B. Michael McCulloch, who led the University of California, Berkeley study, says current therapy for chronic hepatitis B is a drug called interferon alfa.

McCulloch: What we found was the patients using herbal medicine plus interferon had a better outcome than people using interferon alone. So the herbs were basically able to enhance the effectiveness of interferon in treating chronic infection.

Narrator: Overall, the study found that Chinese medicine combined with interferon was twice as effective as interferon alone in reducing hepatitis B viral load to undetectable levels. McCulloch hopes this study promotes broader awareness of eastern medicine's potential to improve the effectiveness of conventional care.

McCulloch: The best role for Chinese medicine is really in combination with conventional care as an adjunctive or complimentary treatment. The obligation is really on both sides, on the conventional western end and the Chinese practitioner's end to really take efforts to work together.

Narrator: For Science Today, I'm Larissa Branin.

B. The Facts about Type 1 Diabetes

Narrator: This is Science Today. In terms of its cost to society, diabetes ranks fourth among diseases. Dr. Jeffrey Bluestone of the Diabetes Center at the University of California, San Francisco, says Type 2 diabetes, which is associated with obesity, is the most common but Type 1, also known as Juvenile diabetes, is on the rise.

Bluestone: This is a disease of the immune system, where your T-cells, which are normally designed to recognize bacteria, viruses, instead are attacking your own body - in this case, the insulin-producing cells in the body.

Narrator: About one million people are affected by Type 1 diabetes - mostly kids between the ages of five and 20. Bluestone says researchers are not quite sure why it's on the rise.

Bluestone: But it's very clear that auto-immune diseases in general and diabetes in particular seems to be growing in First World countries like our own - not in Third World countries interestingly. It's growing to really quite significant proportions and I think a lot of work still needs to be done to figure out what are the precipitating events that cause that.

Narrator: For Science Today, I'm Larissa Branin.

C. How Socio-Economic Status Affects the Diagnosis of ADHD

Narrator: This is Science Today. There have been reports that doctors are overdiagnosing Attention Deficit Hyperactivity Disorder, or ADHD. But researchers studying the disorder say overdiagnosis affects mostly upper and middle class children. Dr. Stephen Hinshaw, a psychology professor at the University of California, Berkeley, says children of lower socio-economic status are actually underdiagnosed.

Hinshaw: There's some reason to think that there might be slightly more ADHD among lower SES families. One of the paradoxes is that the current controversy about overdiagnosis, overtreating these kids, is really a white middle class, upper middle class suburban phenomenon.

Narrator: Hinshaw says the media should address this discrepancy in order to promote better care in less privileged communities.

Hinshaw: There's a disconnect between access to treatments between suburban well-to-do families, who may be in some ways pushing for this diagnosis, and between more of the children who might truly deserve the diagnosis who aren't getting the access to treatment.

Narrator: For Science Today, I'm Larissa Branin.

D. Researchers Work to Improve the Agricultural System

Narrator: This is Science Today. When the rice genome was sequenced earlier this year, it provided researchers with more insight into how genes function in crop plants and a how to develop hardier, more productive varieties through traditional breeding or genetic engineering. Pamela Ronald, a molecular biologist at the University of California, Davis says the agricultural system can always be improved.

Ronald: We need to think about better ways to control pathogens, we need to grow more crops on less land and we want to do this in a sustainable manner. So I think biotechnology is just one tool out of many tools that can contribute to that.

Narrator: In 1995, Ronald isolated the first disease-resistance gene in rice.

Ronald: The resistance gene we work on primarily in my lab is very similar to a receptor that's involved in many different cancers. So if we can make these directed changes, perhaps we can make some big steps in improving agriculture.

Narrator: For Science Today, I'm Larissa Branin.

E. The Role of Female Choice in Animal Mate Selection

Narrator: This is Science Today. It was Charles Darwin who first wrote about female choice in animal mate selection, but biologist Marlene Zuk of the University of California, Riverside, says Darwin's idea of female choice did not sit well with his contemporaries and the idea of female choice dropped away for a long time.

Zuk: It wasn't until I think pretty much the 1960s that people started going back to this. The whole point is, how many genes are you going to leave? You're going to leave genes in the form of offspring - what's going to make that happen?

Narrator: For females of an animal species, that all depends on how many offspring can be physically produced and in many cases, reared.

Zuk: But for the males, what they're limited by is the number of females they can attract to mate with them. And so because of that, you would expect males to in general, compete for access to females because the more they can get females, the more genes of theirs are going to be left in the next generation.

Narrator: Zuk is currently studying the importance of disease resistance in animal evolution. For Science Today, Larissa Branin.

 

 

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