Program 752,
  September 23, 2002

 

A. The Relationship between Host and Parasite Helps Drive Evolution

Narrator: This is Science Today. Researchers led by University of California, Berkeley biologist Thomas Cline, recently discovered that a parasite living on the fruit fly can make sterile fruit flies fertile again. Cline says this unexpected interaction between a parasitic bacteria and its fruit fly host has implications for our understanding of fundamental biological processes.

Cline: To find that infection by a bacterium can restore, can counteract the effects of this single nucleotide change in a particular gene, just shows you how little we know really about the kinds of interactions that go on in the real world, and the kinds of factors that are really very important for evolution.

Narrator: Cline explains that the competition between host and parasite leads to biological change.

Cline: Because it's a constant race-the parasite obviously wants to take advantage of the host, and the host obviously doesn't want to be taken advantage of too much, so there's this constant race, and it's true of humans, it's true of every species on Earth, where there's this constant battle of outracing your parasites.

Narrator: For Science Today, I'm Larissa Branin.

B.The Rice Genome and Genetic Engineering

Narrator: This is Science Today. The recent completion of two sequences of the rice genome give scientists a better understanding of a grain that feeds half the world's population. Pamela Ronald, a molecular biologist at the University of California, Davis, says this basic information is not directly related to the more controversial practice of genetic engineering.

Ronald: This genome sequence can be applied to traditional breeding, which we have been doing for a hundred years. Now, genetic engineering is different because we can take a gene from rice or from another organism and we can engineer it into that plant.

Narrator: Using knowledge about the rice genome for traditional breeding can help farmers grow rice that is more resistant to disease and drought. Ronald says genetic engineering can also be beneficial if the results are carefully monitored.

Ronald: So I think the idea behind both traditional breeding as well as genetic engineering of rice is to really develop improved rice lines that farmers can grow, that taste very good, that have improved nutritional qualities.

Narrator: For Science Today, I'm Larissa Branin.

C. Automating a System for Detecting Biological Attacks

Narrator: This is Science Today. A new system called BASIS has been developed to detect biological agents released in the air by a terrorist attack. Researchers at the Lawrence Livermore and Los Alamos National Laboratories created the network of air monitors and testing labs to protect special events like last winter's Salt Lake City Olympics. But Livermore Project Manager Dennis Imbro says the system could be used beyond special events if certain challenges are met.

Imbro: If we want to take the system and run it 365 days a year in a city, now we become concerned with the crew size. And so one of the specific things that we're doing is automating all the processes. Put it on robotic workstations and making it easier for a few people to push through a lot of samples per day.

Narrator: Imbro says automation involves significant scientific challenges. The samples used to test for biological agents must work perfectly since no person will be present to oversee the process.

Imbro: False alarms in a situation like this are really very unacceptable.

Narrator: For Science Today, I'm Larissa Branin.

D. A Geriatrics Study Looks into Biomarkers for Health

Narrator: This is Science Today. A UCLA-led geriatrics study is looking into how biological markers in the blood may serve as an early identification of disease and functional decline in older, at-risk populations. Dr. David Reuben, chief of UCLA geriatrics, says they're looking at two biomarkers in particular.

Reuben: The first is serum albumin. Serum albumin is a protein that everybody has and it's the same albumin that's in your egg whites. The important thing about this protein is that it's a very, very good predictor of four-year mortality or decline in function.

Narrator: The other biomarker is a cytokine called IL-6 that can predict the presence of inflammation, which is a possible indication of disease.

Reuben: I'm not sure that it's justified in terms of the screening yet at this point and certainly the IL-6, which is a pretty expensive test, would not be justified for screening purposes yet. But that doesn't mean that sometime in the future this might not be the case.

Narrator: For Science Today, I'm Larissa Branin.

E. An Intelligent Car Sharing Program

Narrator: This is Science Today. An automated car-sharing system using electric powered vehicles for short trips is being used and tested by researchers at the University of California, Riverside. Electrical engineer Matt Barth says one of the issues they're looking into is keeping the IntelliShare Community Vehicle Project in balance.

Barth: That we don't have too many vehicles at one station and not enough at another. And these system management techniques we've developed does indeed keep our system in a well-distributed fashion where it continues to function properly throughout the day.

Narrator: Each vehicle has a small microcomputer on board that makes it easy to keep track of its whereabouts and system status.

Barth: Probably the reason it hasn't been so popular as of yet is it adds an extra burden to the user to try to use these types of systems. When there is an added amount of convenience with this technology, then people are going to be able to embrace that and use it much more often.

Narrator: For Science Today, Larissa Branin.

 

 

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