Program 734,
  May 21, 2002

 

A. A New Theory on Human Longevity

Narrator: This is Science Today. People can expect to live longer today than ever before. This is usually chalked up to better medicine and healthier living conditions. But according to James Carey, a professor of entomology at the University of California, Davis, we may have evolution to thank for our longer lifespans.

Carey: We developed this theory on the longevity…orientation toward this with humans. And so when we explore this we find that lifespan extension is what we call self-reinforcing. That is the greater the lifespan, the greater your health is and the better your health is more your life span and so forth.

Narrator: Carey says that longer lifespans allow people to create stronger social bonds and to make the medical discoveries that prolong our lives. He says it's these factors-more than diet and exercise-that will continue to extend the human lifespan.

Carey: There will be things like organ replacement and there will be disease cures. But I feel that down the road we'll have a basic understanding of how to arrest aging at some level.

Narrator: For Science Today, I'm Larissa Branin.

B. What You Should Know about Spinal Fractures

Narrator: This is Science Today. Believe it or not, about two-thirds of spinal fractures are painless. When the vertebrae that make up the spine start to break, they break by becoming compressed. And while this may not hurt, studies indicate people who start to have compression in the spine are much more likely to experience additional fractures. Dr. Steve Harris, chief of the University of California, San Francisco's Osteoporosis Clinic Programs, says the best way to find those subtle, painless fractures is to measure height.

Harris: This is a challenge to you. Think about the last time you were measured - what, age sixteen? It's not really standard practice to measure height in grown-ups, but I would really encourage you the next time you go in for a routine check-up, to have somebody measure your height.

Narrator: If you're a lot shorter than the height you've always gone by, Harris says chances are you're starting to shrink.

Harris: And this is really a call to action. It's worthwhile exploring to see whether your vertebrae really are starting to compress and that's easy to do on an X-ray examination these days.

Narrator: For Science Today, I'm Larissa Branin.

C. Measuring the Effects of Atmospheric Nanoparticles

Narrator: This is Science Today. The term nanotechnology tends to conjure up images of tiny computers. But the air we breathe is full of nanoparticles, which can be measured only on the smallest scale. They are created through all kinds of combustion, including automobiles and factories. According to Dr. Anthony Wexler of the University of California, Davis, these nanoparticles are tiny but can have a huge effect.

Wexler: They affect human health. The EPA estimates that particles of this size kill something like 50,000 people per year in this country from inhaling them. So of course there are big health effects.

Narrator: Because nanoparticles are so small, measuring them has presented scientists with a big problem. But Wexler's team at Davis has the only instrument in the world that can test the size and make-up of nanoparticles one-by-one.

Wexler: And currently we're doing it in Pittsburgh and Baltimore, working with the EPA. There's big measurement programs going on there called the EPA super-sites that measure all kinds of things about particles in the atmosphere. .

Narrator: For Science Today, I'm Larissa Branin.

D. A New Method Helps Scientists Decipher the Book of Life

Narrator: This is Science Today. As one can very well imagine, trying to find all of the genes encoded within the DNA that make up our chromosomes has been a very difficult task. But new technology is helping. At the Lawrence Livermore National Laboratory, scientists developed a process called Gene Recovery Microdissection, which can identify all of the genes that belong to a specific part of each individual chromosome.

Coleman: Even though you hear about we've completed the human genome, if we considered the human genome to be a book, we've kind of found all the words in the book, but we don't exactly understand the chapters and paragraphs and the sentences that link it all together that help us to understand and read the book. And that's what gene recovery microdissection does for you.

Narrator: This technique can even be used to understand bacteria species that can't ever be grown in the lab.

Coleman: We can, without culturing a bacteria in a lab, isolate its DNA, amplify it and clone it so that we can sequence it and understand their entire genome.

Narrator: For Science Today, I'm Larissa Branin.

E. A Call For Better Pain Control

Narrator: This is Science Today. Inadequate treatment of surgical pain is fairly common because hospitals are often wary of overdoing pain medication - especially opiodes. Dr. Daniel Sessler, a professor of anesthesia at the University of California, San Francisco, says this is due to the fear of complications, such as respiratory depression, but there's also a concern about addiction.

Sessler: Addiction is very rarely a problem. Especially with acute pain. It becomes more of an issue with chronic pain, but for acute, surgical pain, there's overwhelming evidence that you can use as much opiode, as much narcotic as necessary, to treat the pain and that people will not become addicted.

Narrator: Sessler discovered sufficient pain control after surgery led to a reduction in the risk of infection. This gives physicians all the more reason to not hold back.

Sessler: People who have pain should be treated and they should be treated even if it's so-called minor pain off in a physician's office or a hospital laboratory. Even that pain deserves to be treated.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu