Program 728,
  April 9, 2002

 

A. The Number One Killer of American Women

Narrator: This is Science Today. In the year 2000, among all deaths of American women, thirty percent was attributed to heart disease. Another nine percent of women died of stroke, so cardiovascular disease as a whole accounts for about forty percent of deaths among women. Deborah Lindes, a professor of medicine at the University of California, San Francisco, says although heart disease is a huge problem for women, it's not recognized as such. Instead, Lindes says women are more concerned about breast cancer, which in comparison, accounts for three percent of female deaths in this country.

Lindes: Cardiovascular disease is the number one killer of women in the U.S. One in ten women in the middle-aged years have heart disease and that goes up dramatically as women age. One in four women over sixty-five have some form of heart disease.

Narrator: And yet, Lindes says women with heart disease don't report their symptoms as readily as men do, so they tend to delay seeing a doctor until later in the course of their disease.

Lindes: Partly because women when they have symptoms, tend to think that - well, this is probably not a heart attack, I'm a woman isn't this a problem for men and attribute their symptoms to other causes.

Narrator: For Science Today, I'm Larissa Branin.

B. Dispelling the Myth of a 'Rootless' Society

Narrator: This is Science Today. There's a tendency to regard today's society as being more on the move and less rooted, geographically, than our great-grandparents were. But historical records indicate the opposite. Claude Fischer, a sociologist at the University of California, Berkeley, says the major reason people moved in the past was because of financial constraints.

Fischer: Farm failed or there were too many people trying to live off the same farm or factory closed down or somebody got flooded out - or people just had economic hard times. They would move from place to place - whether it's from Europe to the United States or within the United States.

Narrator: But Fischer says a lot of those economic pressures have eased as we've become a more affluent and mobile society.

Fischer: Back in the 19th Century, when commuting meant walking basically, if your new job was more than two miles away, you probably would move. Today somebody can change jobs, fifty miles may not make a difference one way or the other, so it's easier to go from job to job today if you stay in the same metropolitan area and stay in the same neighborhood.

Narrator: For Science Today, I'm Larissa Branin.

C. How Menopausal Women Can Keep Their Estrogen Levels

Narrator: This is Science Today. About two-thirds of women who get breast cancer after menopause can trace the disease to higher-than-normal levels of estrogen. Previous studies have shown a close link between high levels of estrogen and a higher risk for breast cancer. Dr. Steven Cummings of the University of California at San Francisco is trying to find ways to prevent the onset of estrogen-related breast cancer. Some scientists have recommended a low-fat diet.

Cummings: Unfortunately, most studies have shown no benefit to reducing fat unless you also reduce your weight. Weight loss may reduce your risk so if you reduce the fat level in your diet you may lose weight and that may cause a reduction in your risk of breast cancer.

Narrator: Cummings says women should concentrate on keeping their estrogen levels very low. Since higher estrogen levels are found in heavier women, weight loss is one possibility.

Cummings: So, it can't be explained entirely by the effects of hormones but it's one rational explanation-that by losing weight you might reduce your estrogen level.

Narrator: For Science Today, I'm Larissa Branin.

D. An Asthma Study with Major Public Health Implications

Narrator: This is Science Today. Since the late 1980s, rates of asthma - especially in children - have been greatly rising. Kathleen Mortimer, an epidemiologist at the University of California, Berkeley has recently found children born prematurely or of low birth weight, are the most susceptible to smog-induced asthma.

Mortimer: This was the first study that identified that as a susceptible subgroup as far as I know. I mean, there's been lots of evidence that in general, children of low birth weight have more respiratory problems throughout life and it lasts even until adulthood. But this was the first one that looked particularly at air pollution.

Narrator: This study may have major public health implications because this higher susceptibility doesn't just affect asthmatic children….

Mortimer: It may be that in the general population, children who were born low birth weight or premature also show this greater response and that has a bigger public health impact because in general, only less than ten percent of the population has asthma. But if worldwide or nationwide, children even without asthma are greater responders if they're premature, then it hits a bigger population.

Narrator: For Science Today, I'm Larissa Branin.

E. Technology that Detects Tooth Decay in Early Stages

Narrator: This is Science Today. The tools dentists most commonly use to detect early tooth decay are the metal probe and the x-ray. Daniel Fried of the University of California, San Francisco's Department of Preventive and Restorative Dental Sciences, says these procedures are effective, but they don't detect decay in its earliest stages.

Fried: What I mean by the very early stages is when it's confined to the outer enamel layers because once it penetrates down to the underlying dentin, the dentin dissolves very fast and so the decay just blooms out underneath the enamel. So it can cause what a dentist would call hidden caries.

Narrator: Fried and his colleagues are working on various types of laser technologies to provide a tool that can detect decay in these early stages.

Fried: One of the tools that we're working on is called optical coherence tomography. This is a tool that uses optical fiber technology - so, it basically has a fiber probe that you could stick into one of these pit and fissure areas or scan across the surface of the tooth and it measures changes in light scattering.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu