Program 726,
  March 25, 2002

 

A. Laser Dentistry: Something to Smile About

Narrator: This is Science Today. Laser dentistry is an exciting innovation in dental care -especially for patients who may cringe at the sight and sound of the drill. Dr. Daniel Fried of the University of California, San Francisco's Division of Preventive and Restorative Dental Sciences, says within the past five years, the first FDA-approved lasers in dentistry have been used to treat gum disease and cavities.

Fried: The primary advantage of using a laser is that there's no noise and vibration associated with the laser like the drill. And that actually translates to pain. So there's less pain associated with the procedure - it's not completely painless, but there is considerably less pain.

Narrator: Fried and his colleagues have been studying the laser's ability to render tooth enamel resistant to acid dissolution, which could lead to tooth decay.

Fried: So that's another advantage - you can render the walls resistant to further acid dissolution. So you could treat high-risk areas like in you molars, you have these little pits and fissures and that's primarily where dental decay occurs today.

Narrator: For Science Today, I'm Larissa Branin.

B. Concern over Fine Particle Air Pollution

Narrator: This is Science Today. A recent NYU School of Medicine study has found that fine particle air pollution significantly raises the risk of dying of lung cancer or other lung and heart diseases. While the Environmental Protection Agency has issued rules regulating this type of pollution, Lara Gundel, a scientist at the Lawrence Berkeley National Laboratory, says there's been some debate.

Gundel: Because the generators of the particles are typically industries and they would like to have as little regulation as possible. They don't want to have onerous regulations. So there has been controversy about what level should be regulated and what's the scientific basis for the regulations in the Clean Air Act.

Narrator: At the Lab, Gundel has developed a novel air sampler that may shed more light on these atmospheric pollutants.

Gundel: I guess the innovations we made were a way to separate the gases and particles accurately and then to be able to collect and measure the particles and the gases separately and accurately.

Narrator: For Science Today, I'm Larissa Branin.

C. Fish Consumption and Mercury Contamination

Narrator: This is Science Today. Centers for Disease Control and Prevention data indicates that 10 to 15 percent of American women of childbearing age have mercury blood levels that exceed current EPA safe levels. This data compelled the FDA to warn pregnant women about which fish to avoid to reduce mercury contamination. Russ Flegal, an environmental toxicologist at the University of California, Santa Cruz, says mercury bio-accumulates and so it's the large fish that have the highest concentrations of mercury.

Flegal: And those are the food fish that people eat. 034 Of the fish, swordfish is the one that typically has the highest concentrations of mercury and there are warning out on swordfish that you should only eat it once or twice a month at most because of the high levels of mercury in it.

Narrator: But Flegal says that doesn't mean people should avoid eating fish.

Flegal: Fish is a terrific source of protein and so to say that people shouldn't eat fish, the disadvantages of that may outweigh the advantages of getting that protein source. You simply need a balanced diet and need to make sure you're eating different types of fish with different levels of mercury in them.

Narrator: For Science Today, I'm Larissa Branin.

D. A Changing Medical Landscape for HIV Patients

Narrator: This is Science Today. Thanks to anti-viral drugs, people who are HIV positive are living longer than ever before. Dr. Michele Roland of the University of California, San Francisco is conducting a long-term study to find out whether organ transplants are safe and effective in HIV-positive patients who have other medical problems.

Roland: The fact that we're looking at transplantation for people with HIV is sort of indicative of a broader issue for people with HIV. And that is that as our therapies are improving and people are living longer, we're seeing a population that's aging. And an aging population develops an increasing number of medical problems.

Narrator: According to Roland, this means that doctors must change the way they treat their patients with HIV.

Roland: And we're dealing with having to, as HIV care providers who have specialized more and more in a non-general medicine field, kind of go back and relearn our general medicine so we can treat people with these common diseases.

Narrator: For Science Today, I'm Larissa Branin.

E. Researchers Aim to Develop Treatment that Blocks Addictive Behaviors

Narrator: This is Science Today. Drug addiction has always been very hard to treat-partly because the science behind it is still poorly understood. Now scientists at the University of California, San Francisco have discovered one reason drugs can take such a strong hold on an addict's brain. Dr. Antonello Bonci found in test subjects that a significant change occurs in the brain after just one exposure to cocaine.

Bonci: What is also incredible for us is that this phenomenon lasts for up to five days. And this very short exposure to cocaine, we have estimated that the rat and the mice will experience cocaine in their blood for a few hours.

Narrator: This change creates a kind of cellular memory, which allows the brain to make decisions based on getting more of the drug.

Bonci: The idea that we want to emphasize is that if we can understand the series of events that change, maybe we'll be able to design drugs that will interfere with the development of the addictive behaviors by blocking the functional changes.

Narrator: For Science Today, I'm Larissa Branin.

 

 

Science Today is produced by the University of California
  Office of the President
and broadcast over the CBS Radio Network

For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu