Program 716,
  January 15, 2002

 

A. The Continuing, Deadly Threat of Tuberculosis

Narrator: This is Science Today. It's estimated that a third of the world's population is infected with tuberculosis - and that figure includes about 15 million Americans with a latent form of the bacterium. Joel Ernst, an infectious disease specialist at the University of California, San Francisco, says for years TB was thought to have been conquered.

Ernst: It certainly fell from the American consciousness, at least most of American's consciousness, after about the 1950s or so. Tuberculosis sanitaria were closed because they weren't necessary anymore. Anti-tuberculosis treatment was given as an outpatient and most people with tuberculosis who received those drugs were cured.

Narrator: Today however, stealthy strains of the microbe that causes TB have brought the disease back to pre-antibiotic days in many parts of the world, including New York and other parts of this country.

Ernst: The best chance of defeating it is going to be through the development of a more effective vaccine.

Narrator: Public health officials are also calling for better education about the disease. For Science Today, I'm Larissa Branin.

B. What to Do Before Spraying Insecticides

Narrator: This is Science Today. Those who aggressively spray insecticides to combat what they perceive as plant or landscape-damaging insects may be doing these plants - not to mention the environment - a great disservice. Mary Louise Flint, an integrated pest management expert at the University of California, Davis says often times holes in plants leaves or brown spots in lawns are caused by underwatering plants or using other incorrect practices.

Flint: They'll go to the retail nursery and buy an insecticide and apply it without even looking to see if whether there is an insect there causing that damage.

Narrator: So Flint recommends taking a closer look at what's going on in your garden or landscape before heading out to the store for insecticides. And even then, Flint says you may need to do some homework.

Flint: First of all, you need to determine whether there is an insect on your plant that is causing damage. People will spray for beneficial insects, too, not recognizing that they are good.

Narrator: For Science Today, I'm Larissa Branin.

C. Lupus: The Facts about this Autoimmune Disorder

Narrator: This is Science Today. Lupus is an autoimmune disease in which the body basically turns against itself. It affects women nine times more than it affects men and is three times more common in women of color than in Caucasians. John Davis, an assistant director of the University of California, San Francisco's Clinical Trials Center says making the diagnosis is often times difficult because the symptoms can be confused with other illnesses.

Davis: As an example - cancer, chronic infections can cause the same type of symptoms that lupus causes. Some medications can even cause a drug-induced type of lupus. So the way to make the diagnosis is to be seen and evaluated by a rheumatologist.

Narrator: Some of the most common telltale signs of lupus are fatigue, skin rashes, photosensitivity and kidney or blood disorders.

Davis: Each patient is an individual with the disease. Not every patient acts the same even though they have the same diagnosis. So even though they all have the same diagnosis, there are different manifestations going on within each patient.

Narrator: For Science Today, I'm Larissa Branin.

D. A Hardy Way to Deal with Stressful Times

Narrator: This is Science Today. In the aftermath of the September 11th terrorist attacks, many people have been dealing with a range of emotional and financial stress. Dr. Salvatore Maddi, a psychologist at the University of California, Irvine, says how a person deals with stress is not an inherent skill - it can be learned. In fact, Maddi trains patients to develop what he calls 'hardiness' skills.

Maddi: We think of it as a combination of attitudes and skills that help you cope with stressful circumstances, whether the stresses are big or small. The attitudes are what we came to call the three C's - commitment, control and challenge.

Narrator: There are also coping and social support skills. The hardiness program is based on a 30-minute survey Maddi developed and extensive research.

Maddi: The research has also concerned itself with evaluating the effects of our hardy training and it shows that the hardy training really works in the sense that it increases hardiness, but in addition, it improves performance, conduct, morale and health.

Narrator: For Science Today, I'm Larissa Branin.

E. Non-invasive Methods Gauge How Substance Abuse Affects the Brain

Narrator: This is Science Today. Magnetic resonance imaging and another method called magnetic resonance spectroscopy have been helping researchers non-invasively study the brain to better understand its functioning in a variety of circumstances. Dieter Meyerhoff, a radiologist at the University of California, San Francisco, has been using these methods to study how the brain is affected by alcohol abuse and recovery from alcohol.

Meyerhoff: We're also looking at how alcohol itself interacts with the damage that is done by either HIV infection or substance abuse.

Narrator: Overall, Meyerhoff says the big question they're asking is how substance abuse affects the brain and how does it interact with other problems.

Meyerhoff: And that is a big problem doing what we call pure alcohol research - finding patients who have abused nothing else than alcohol. There is a lot of other abuse occurring at the same time and very often, there are many other disorders that we need to rule out if we want to look at the pure effects of alcohol.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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