Program 709,
  November 27, 2001

 

A. Discovering a Treasure Trove of Drugs in the Sea

Narrator: This is Science Today. Small marine animals called bryozoans commonly live on the bottoms of boats, piers and rocks underwater. Because of this, researcher Margo Haygood of the University of California, San Diego's Scripps Institution of Oceanography, says in the past, these organisms were considered a nuisance and a lot of funding was spent to try and get rid of them.

Haygood: It was in the 1960s that a group began to screen invertebrates for anticancer activity and discovered it in this very well known, very familiar organism. And since then, there's been a great deal of research on the compounds that are found in this animal and they do have tremendous promise for treating cancer.

Narrator: Haygood and her colleagues isolated the bacteria within these organisms that produces the anticancer compound and are now working on methods to commercially supply this compound.

Haygood: If we can use the kinds of methods that we're using here, we can unlock that potential and take advantage of the biological diversity of the ocean for treatment of human problems.

Narrator: For Science Today, I'm Larissa Branin.

B. The Art of the Deceptive Smile

Narrator: This is Science Today. We all know the feeling. The conversation lulls, leaving a heavy, uncomfortable silence. You flash a smile across the table and get a nervous grin in response. But what do those upturned corners really mean? Doctor Paul Ekman, a psychology professor at the University of California San Francisco says they are one of several "deceptive" smiles that humans constantly deploy.

Ekman: The false smile is made to deliberately mislead another person to make them think that you're enjoying yourself when in fact your not.

Narrator: Ekman says deceptive smiles are used to hide our true feelings, and are difficult to distinguish from genuine smiles of enjoyment.

Ekman: Most of us are really not able to tell whether someone is lying to us or not, even if it's a very serious lie, and I believe most of don't really want to know anyhow. And besides which, who wants to go through life being suspicious all of the time about whether someone is misleading us?

Narrator: For Science Today, I'm Larissa Branin.

C.The Far and Wide Reach of Tsunamis

Narrator: This is Science Today. Tsunami is a Japanese word that means "harbor wave". Casey Moore, a professor of Earth Sciences at the University of California, Santa Cruz says tsunamis - which are sometimes called tidal waves - are caused by earthquakes, underwater landslides, volcanic eruptions or impact from meteorites.

Moore: In any case, if it's a landslide or a tectonic earthquake-related movement, the water surface gets disturbed and that wave moves out and propagates.

Narrator: Although tsunamis are not very frequent, when they do occur, they tend to be quite notable since they can travel long distances.

Moore: For instance, the earthquake in 1964 in Alaska - the tsunami devastated Eureka, California. It came because of the ocean bottom and the wave came in and focused there and there was a substantial amount of damage.

Narrator: Moore is part of an international research team that's working to improve risk assessment of catastrophic earthquakes, which can trigger tsunamis. For Science Today, I'm Larissa Branin.

D. Do Cells Commit Suicide?

Narrator: This is Science Today. Strokes are caused by interrupted blood flow to the brain and can often result in massive injury to the brain's neurons. After the initial injury, the cells often try to repair their damaged DNA. The process is extremely taxing, and can sometimes kill the neuron. But Doctor Raymond Swanson, a neurology professor at the University of California, San Francisco, says the process may simply be a way for cells to self-destruct.

Swanson: Cell death in a stroke is not purely a passive process. The thinking for many years is that when cells in the body, and especially in the brain are deprived of blood, they simply run out of energy and die, and there's nothing that can be done about it. Our data shows that the cells themselves contribute to their own death.

Narrator:But Swanson says the process isn't just a cellular suicide mission, but rather a glitch in cell responses to massive trauma.

Swanson: And so what we think is going on is that this is a normal response to DNA damage, which is simply maladaptive.

Narrator: For Science Today, I'm Larissa Branin.

E. Researchers Strive to Better Understand Gamma Ray Bursts

Narrator: This is Science Today. The Center for Supernova Research at the University of California, Santa Cruz does more than just investigate massive explosions known as supernovae. Stan Woosley, a professor of astronomy and astrophysics who directs the center, says they're interested in all violent explosions that stars produce.

Woosley: So we study something called gamma ray bursts as well, and I think our group has the leading model for what they are. Gamma ray bursts are a very interesting subject. The observed phenomena has been with us ever since the early 1970s and I guess about one of those happens a day - but you can't see them on the Earth. So they weren't discovered until satellites went up in space, saw a gamma ray emission.

Narrator: What you see is a sudden, very intense flash of light.

Woosley: Trying to understand how something the size of a star can do this has been a major theoretical challenge and we think now that they have something to do with supernovae - that the same engine that powers supernovae also powers gamma ray bursts - maybe with a slight difference.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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