Program 707,
  November 13, 2001

 

A.Marine Bacteria May Lead to a New Source of Anti-Cancer Drugs

Narrator: This is Science Today. A bacteria living inside a small marine animal may be the source of a new drug compound that can be developed to fight cancer. Margo Haygood, a researcher at the Scripps Institution of Oceanography at the University of California, San Diego, says this anticancer compound is found inside a bryozoan.

Haygood: A bryozoan is an animal - it looks like a plant but it's actually a colonial animal, which means it has many small individuals that all live together. The amazing thing about it is that even animals that are considered a nuisance like this, because it grows on boats, can still be full of surprises and still have very worthwhile human uses.

Narrator: Haygood identified a gene that produces the anticancer compound and will now be exploring ways to grow the bacteria outside these marine animals.

Haygood: Since we have been able to find the genes of the right sort, we are cloning out the whole biosynthetic pathway to make the compound to be able to make lots and lots of it so that we can have as much as we need for being able to treat disease.

Narrator: For Science Today, I'm Larissa Branin.

B. Informally Analyzing the Smiles of National Leadership

Narrator: This is Science Today. Doctor Paul Ekman, a psychology professor at the University of California, San Francisco, has studied human facial expressions for over forty years. In the wake of the September eleventh attacks, he now finds himself informally applying his expertise to some national leaders, including Homeland Security Director Tom Ridge.

Ekman: Sometimes when I watch television, I see the kind of smile that Ridge shows when he talks about the latest threat or about the latest person who's gotten Anthrax, well then I'm looking very carefully to see what kind of smile is he showing?

Narrator: Ekman says what he sees are smiles that simultaneously convey gravity and reassurance - which can be a bit confusing.

Ekman: None of that's being deliberately deployed. Even these social smiles, these polite ones, the tactful ones, the agreement ones, we do those without thinking, they've become a habitual part of our conversational style. It's their absence that might worry us, not their presence.

Narrator: For Science Today, I'm Larissa Branin.

C. Seeking Clues to the Cause of the Most Powerful Earthquakes

Narrator: This is Science Today. An international group of scientists, including Casey Moore, a professor of earth sciences at the University of California, Santa Cruz, are seeking to understand the cause of the most powerful earthquakes. Moore, one of the chief scientists leading the research project, says they're using special drilling technology from the oil industry to measure and monitor physical properties of a fault zone off the shore of Japan - and they're doing it in place.

Moore: So that it's like instead of measuring the density or the porosity of something that's removed from its original environment, you measure right where it is and you get a truer sense of its behavior.

Narrator: In particular, Moore says they're looking at fluids flowing along fault zones.

Moore: We want to use the nature of the fault zones and the fluids as a monitor for movement of the fault because when the Earth is stressed, when there are forces on it, it behaves like a sponge and it starts to squeeze out some of the water. So at this stage, people are just trying to understand how the faults behave.

Narrator: For Science Today, I'm Larissa Branin.

D. The Evolutionary Advantages of Sexual Reproduction

Narrator: This is Science Today. Evolutionary biologists have wondered for years just why sexual reproduction is more common than asexual reproduction - especially since asexual populations have the advantage of producing more offspring. Now, researchers at the University of California, Santa Barbara, have demonstrated for the first time that the accumulation of beneficial mutations is faster in sexual populations. Biologist Marlene Zuk, of the University of California, Riverside, has also done work in this field and says that's because sexual reproduction provides more variation in offspring.

Zuk: You make fewer of them and they're not as much like you, but what if they're better? Let's say that you're in a population where there's some disease that's attacking everybody. Well, parasites are doing this because they're able to exploit some aspect of your genotype. Let's say they can do better to attach to your intestinal lining. Well, if you have a bunch of offspring that vary in the quality of their intestinal lining, then maybe one of them is going to be able to resist the pathogen.

Narrator: For Science Today, I'm Larissa Branin.

E. A Little Common Sense Goes a Long Way in Reducing Heart Disease

Narrator: This is Science Today. Americans have dramatically reduced their risk of dying from heart disease by using a little common sense. This according to Doctor Lee Goldman, a researcher at the University of California, San Francisco who found that Americans are living longer simply by smoking less, eating healthier and lowering their cholesterol.

Goldman: Every now and again, what your mother told you to do was right. And our paper really emphasizes the tremendous public health benefit of healthy living and paying attention to some of the most basic of risk factors. It doesn't seem like rocket science, but the benefit to the U.S. population is really very substantial.

Narrator: And Goldman says his research shows that ongoing efforts should have reasonably similar benefits.

Goldman: Our analyses suggest that really simple preventative measures probably explain half or more of the decline in heart disease mortality in the U.S.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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