Program 688,
  July 3, 2001

 

A. A Study Questions Age-based Cancer Screenings for the Frail Elderly

Narrator: This is Science Today. A new study questions the practice of routinely encouraging elderly women in poor health to have mammograms. Dr. Louise Walter of the University of California, San Francisco, says their study suggests age-based cancer screening guidelines should be more individualized.

Walter: The idea was to try and bring screening more into thinking about the benefit and the risk in involving patient preferences in the decision, as opposed to just screening to a certain age and then stop - based on some guideline that you read.

Narrator: Walter says that's because there's so much variability in older patients.

Walter: For example, if you have a very healthy eighty-year old person - life expectancy of this person is going to be at least ten years. And they're therefore likely to benefit from screening, because usually screening's meant to detect something that occurs five to ten years down the road. So it's generally agreed that you have to have a five to ten year life expectancy if you're going to get any benefit from a cancer screening test. So you could see that person as potentially benefiting as opposed to a seventy-year old with severe congestive heart failure.

Narrator: For Science Today, I'm Larissa Branin.

B. An Innovative Way to Measure Heavy-duty Diesel Emissions

Narrator: This is Science Today. Measuring emissions generated from engines under "real world" operating conditions is difficult because the results can vary greatly. But researchers at the University of California, Riverside are now using a high-tech, lab-on-wheels to measure the emissions produced by heavy-duty diesel engines. Joe Norbeck is director of the university's Center for Environmental Research and Technology.

Norbeck: We've put together an emissions laboratory that's unique in the world. We took a fifty-five foot trailer that you see driving along these large trailers that heavy-duty diesel engines pull and we put a very elaborate and sophisticated emissions laboratory inside this 55-foot trailer.

Narrator: The diesel tractors then pull around this trailer, while instruments inside take detailed measurements of the composition of the exhaust.

Norbeck: We're now going to not only be able to understand better the emissions of the current vehicle fleet, but to see what the impact will be with control strategies.

Narrator: For Science Today, I'm Larissa Branin.

C. Can Consumers Avoid G.M.O.'s?

Narrator: This is Science Today. As the controversy over genetically modified organisms, or G.M.O.'s, continues to swirl, one thing is clear - it's becoming almost impossible for consumers to avoid them. Norman Ellstrand, a professor of genetics at the University of California, Riverside, says it would be hard to avoid eating food in this country that doesn't have some portion that was genetically engineered in the last twenty-four hours.

Ellstrand: All our processed food has items in them from soybeans and corn, which the vast majority of both crops in the United States are genetically engineered now, so it's very likely that if you eat processed foods, you're going to contact something that's genetically engineered.

Narrator: Regardless of one's opinion of G.M.O.'s, Ellstrand emphasizes it's an important industry and people need to educate themselves on the topic.

Ellstrand: I think the other thing I would emphasize is nobody should listen to one person, that scientists are all specialists and each of us specialists - like the blind men of India - touch a different piece of the elephant and come up with a different view. The best way to get educated is to seek a lot of information.

Narrator: For Science Today, I'm Larissa Branin.

D. Clinical Trials Begin for a New 'Bionic Ear'

Narrator: This is Science Today. A new cochlear implant called the Bionic Ear is set to begin clinical trials at the University of California, San Francisco and other leading medical centers nationwide. Jan Larky, an audiologist at the university, says the study is targeting adults with profound hearing loss.

Larky: Even though the implant may not give somebody perfect hearing, this implant really has the ability to allow people to connect with other people through communication and most of these people will come in and say, "I can't communicate with my family. I feel totally isolated socially, because I can't hear them".

Narrator: Aside from these feelings of isolation, Larky says these implants greatly impact feelings of safety.

Larky: Many people live alone and with an implant you can hear if somebody's knocking on your door. Sounds around the house that are normal and not normal. So there's a certain amount of safety that comes from being able to hear.

Narrator: Those interested in the Bionic Ear trial should contact their local audiologist. For Science Today, I'm Larissa Branin.

E. A Better Understanding of non-REM Sleep

Narrator: This is Science Today. A recent University of California, San Francisco study linking sleep to significant early brain development, has uncovered an interesting finding. According to the study's lead investigator, Dr. Marcos Frank, their results suggest it's non-rapid eye movement, or non-REM sleep, that seems to be important in this process.

Frank: This seems a little counter-intuitive for most folks because people tend to think of rapid eye movement sleep as where all the business must be with sleep because the brain looks very much like waking during this time - there's lots of activation of the brain.

Narrator: But Frank says their results don't rule out a role for REM sleep in the process of learning and memory.

Frank: What they really show is that it's the deep kind of slumber, where the brain is firing in a very peculiar way during this time. It's firing in an synchronized, bursting sort of way, so the whole brain is oscillating on and off and we think that this reverberation activity through the circuits is responsible for the strengthening of the effects of prior waking experience.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu