Program 677,
  April 16th, 2001

 

A. Certain Ethnic Groups Benefit from Earlier Screening for Colorectal Cancer

Narrator: This is Science Today. Currently, early detection screenings for colorectal cancer are recommended for everyone at age fifty and above. But a new study has found for certain racial and ethnic groups, the recommended age should be lower. Dr. Charles Theuer of the University of California, Irvine, led the study.

Theuer: We looked at race in terms of black, Asian, white and Latino and we found that blacks are at highest risk of colorectal cancer and for that reason, they benefit most from a screening program that starts even before age fifty.

Narrator: In their study - the first of its kind to look into the cost-effectiveness of screenings in certain groups, the age that proved most effective for African-Americans was forty-two.

Theuer: Regardless of race, everyone needs to be screened starting at age fifty. And that's really an important point because a recent study showed that less than ten percent of our population is being screened in accordance with current American Cancer Society guidelines.

Narrator: For Science Today, I'm Larissa Branin.

B. A Link Between High Cholesterol and Osteoporosis

Narrator: This is Science Today. High cholesterol has always been associated with heart disease, but UCLA researchers have discovered unhealthy eating and high cholesterol may also contribute to the development of osteoporosis. Farhad Parhami, the lead author of this study, explains.

Parhami: In comparative studies that we were doing, looking at the effects of cholesterol and cholesterol oxidized products, we found that it seems that these agents inhibit the ability of osteoblasts, which are the cells that normally make bone, to function properly.

Narrator: The researchers noticed people with cardiovascular disease also seemed to be at greater risk of developing osteoporosis.

Parhami: Nobody has ever made a link between the two diseases suggesting there may be a common factor and maybe if we find ways to combat cardiovascular disease in a better way, maybe we can actually use those same means to combat osteoporosis.

Narrator: For Science Today, I'm Larissa Branin.

C.The Intriguing Web that Spiders Weave

Narrator: This is Science Today. At this very moment, there's probably a spider somewhere in your home spinning its web. And according to researchers at the University of California, Riverside, some species have been using the same spider silk proteins for at least 125 million years. Dr. Cheryl Hayashi, a professor of biology, says another spider silk protein they've genetically sequenced, dates back about 250 million years.

Hayashi: That's a really long period of time. I mean, we're going back to the Mesozoic, when dinosaurs are walking around. And so this is a long time for these sequences to be conserved. And to us, that argues that these regions of the sequence are probably very important for the functioning of spider silks.

Narrator: Hayashi says there's lots of interest in creating synthetic spider silks.

Hayashi: Spider silk is very strong and very tough. It actually surpasses a lot of the common man-made materials. It's stronger than high tensile steel and has a toughness that is greater than Kevlar. So there's a lot of interest in being able to mass produce spider silk.

Narrator: For Science Today, I'm Larissa Branin.

D. Understanding Managed Care Plans

Narrator: This is Science Today. A health care watchdog organization recently found that although nearly half the nation's premature deaths were linked to such preventable causes as unhealthy diet, lack of exercise or substance abuse, few managed care plans routinely offer services to change these behaviors. Kathryn Phillips, a health services researcher at the University of California, San Francisco, says managed care plans historically haven't offered these services.

Phillips: Often because they don't see the results - the members changed plans before the plan can reap the benefits of a behavior change and it's sometimes much more difficult to provide that type of in-depth preventive service than it is to provide a simple screening procedure.

Narrator: Phillips cautions against thinking of managed care as one monolithic type of health plan.

Phillips: These days, most plans have some type of managed care feature, so we need to learn to think more specifically about what the characteristics of specific plans are.

Narrator: For Science Today, I'm Larissa Branin.

E. What Doctors Need to Know about Pain

Narrator: This is Science Today. There are over two million deaths a year in the United States and more than half of these deaths occurs in hospitals. Steve Pantilat, a hospitalist at the University of California, San Francisco, says up to forty percent of people, regardless of the illness they had at the time of death, suffered moderate to severe pain.

Pantilat: These are people who are hospitalized. They're being cared for in an intensive care unit, so they had plenty of access to medical care and yet, they had moderate to severe pain at the end of life.

Narrator: A previous study found one of the reasons for this was the doctors' inability to adequately assess pain. In his own research, Pantilat, found doctors who simply believed their patients were in pain, were better at controlling it.

Pantilat: What I say to doctors when I teach about this is believe the patient. We have no way to measure whether someone is in pain. There's no machine. There's no blood test to tell whether or not a person is in pain. And in particular, people who have chronic pain, those people don't even look like they're in pain. And yet, what we know is that we're not very good at telling and we have to believe the patient.

Narrator: For Science Today, I'm Larissa Branin.

 

 

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