Program 654,
  November 7, 2000

 

A. The Link between Stress & Abdominal Fat in Lean Women
B.The Most Distant Gamma-Ray Ever Detected
C. Understanding Cellular 'Cross-Talk'
D. Lab Proposes Durable Materials for Nuclear Waste Storage
E. There Is a Positive Side to the 'Terrible Twos'


A. The Link between Stress & Abdominal Fat in Lean Women

Narrator: This is Science Today. A new study has found that lean women with chronic stress are more likely to have an excess of abdominal fat. Elissa Epel, a University of California, San Francisco researcher who led the study, says stress produces the hormone cortisol, which is linked to abdominal fat accumulation.

Epel: This stress response is not harmful in itself and cortisol in fact protects us from part of the stress response. It's very healthy and important. The problem is when stress becomes chronic, the cortisol itself becomes harmful to our health and has negative direct effects and one of these direct effects it can have is increasing the abdominal fat and abdominal fat itself plays a role in many types of disease.

Narrator: Aside from serving as a warning sign, Epel says this knowledge is a topic the diet industry should pay more attention to.

Epel: Because hormones have a lot to do with whether fat's going to stay inside the cells or be mobilized and be able to be burned off so that you can lose weight.

Narrator: For Science Today, I'm Larissa Branin.


B. The Most Distant Gamma-Ray Burst Ever Detectedn

Narrator: This is Science Today. NASA's Ulysses spacecraft recently detected the afterglow of the most distant gamma ray burst ever observed. Research physicist Kevin Hurley of the University of California, Berkeley's Space Sciences Laboratory, was the principal investigator of this experiment. Hurley says this gamma ray burst originated from a gigantic dying star more than 30 times larger than the sun, which exploded 11 billion years ago.

Hurley:The farther back you can look, the more interesting it gets because the closer we're getting to the Big Bang. So not only are we learning about what went on in terms of the star formation in these early galaxies, but we're also learning what the early universe was like outside of those galaxies between us and the galaxies.

Narrator: If these powerful explosions went off in our own galaxy fairly close, it would be the end of civilization on Earth.

Hurley: So it's one more thing that you have to think about when you think about life evolving and in distant galaxies. Were solar systems subjected to a gamma ray burst? Used to be all you had to worry about was comet impacts and asteroid impacts, but now there's something else. So these are the sorts of things you learn when you study these distant objects.

Narrator: For Science Today, I'm Larissa Branin.


C. Understanding Cellular 'Cross-Talk'

Narrator: This is Science Today. When you think about how a cell is constantly bombarded by chemical messages, the big question is how are these messages ultimately 'heard' as a single command. Keith Yamamoto, chairman of molecular and cellular pharmacology at the University of California, San Francisco, says this puzzle raises a real challenge.

Yamamoto: How do two signals work together? How do four? How do eighteen work together? And so the question of physiology - and in the end, disease - is going to come down to understanding how it is that multiple signals work together, to give rise to what comes out in the end in a particular cell that we're examining or the particular cell that is in a disease state.

Narrator: Yamamoto's lab recently deciphered a chemical pathway that determines the survival of immune cells.

Yamamoto: There are specific things about the immune system that we can take away from this bit of knowledge, but as basic scientists, one of the more exciting parts about it is not so much necessarily the application, but that it gives us a way of thinking about how the complexity can be built up.

Narrator: For Science Today, I'm Larissa Branin.


D. Lab Proposes More Durable Materials for Nuclear Waste Storage

Narrator: This is Science Today. Radioactive waste decays over time and this poses long-term storage problems because materials currently used to encase radioactive waste are ultimately damaged and are then susceptible to rupturing or leaching. Scientist Kurt Sickafus of the Los Alamos National Laboratory says one of the major limitations of long-term storage has been the absence of a material that is both chemically durable, as well as radiation-resistant.

Sickafus: They need to be tolerant of the damage that's introduced by the radioactive decay and this is something that is a very difficult problem to solve to have a material that's robust over very long periods of time.

Narrator: But researchers at the Los Alamos Lab have proposed materials - a set of crystalline-ceramic oxides - which appear to have a very high radiation tolerance.

Sickafus: They do appear very attractive. So you're essentially relying on the high stability of these rock-like oxides to hold your radioactive constituents and keep them out of any environmental situations where they would come back to interact with the living environment.

Narrator: For Science Today, I'm Larissa Branin.


E. There is a Positive Side to the 'Terrible Twos'

Narrator: This is Science Today. Most parents have no doubt heard about, and perhaps feared, that time in a child's life coined "the terrible twos". Alison Gopnik, a psychology professor at the University of California, Berkeley says as exasperating as toddlers can be during this rebellious period, it's a time that's crucial to their cognitive development.

Gopnik: What we've done is a bunch of very careful experiments to show that between the time babies are born and the time they're about four, they're changing their ideas about how other people work in very regular and systematic ways.

Narrator: This is done during everyday interactions with people.

Gopnik: So, you can think of the terrible twos as being a kind of experiment that comes when you're eighteen months old and you suddenly get this new, startling hypothesis about other people which is, "my God, maybe sometimes they don't want the same thing that I do! Let me check this out and test out ideas - especially about how other people work.

Narrator: For Science Today, I'm Larissa Branin.

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu