Program 653,
  October 30, 2000

 

A. Physicists Discover the First Direct Evidence of an Elusive Particle
B. A Positive Relationship Between Pain and Inflammation
C. What's Behind the Upward Trend in Maximum Human Life Span?
D. A Small Telescope with Big Implications
E. Is Alzheimer's Disease Intrinsic to Aging?


A. Physicists Discover the First Direct Evidence of an Elusive Particle

Narrator: This is Science Today. A team of physicists recently discovered the first direct evidence of the elusive tau neutrino, a virtually mass-less component of matter. Phil Yager, a physicist at the University of California, Davis, who participated in the experiment, says the word 'neutrino' comes from 'neutrolino' which means 'little neutral one' and refers to the particle's having no electric charge and barely any interaction with surrounding matter.

Yager: They travel typically all the way through the Earth without interacting or longer. So they're very, very hard to discover. You need lots and lots of them and you need a sensitive device.

Narrator: Previous research had established there were two other types of neutrinos and twenty-five years ago, a partner of the tau neutrino was discovered, called the tau lepton. Now that the tau neutrino has actually been detected, Yager says the stage is set to build other experiments that may go beyond the Standard Model of elementary physics.

Yager: As I always like to say, it won't cure male pattern baldness or anything like that, but it's understanding they way the world works and there's hardly anything more exciting than that.

Narrator: For Science Today, I'm Larissa Branin.


B. A Positive Relationship Between Pain and Inflammation

Narrator: This is Science Today. Physical pain is not an experience many of us consider positive, but it does have its good points. Not only does it alert our body to possible danger, but researcher Holly Strausbaugh of the University of California, San Francisco says pain also seems to prevent the body from slipping into states of chronic inflammation.

Strausbaugh: Inflammation is the body's first line of defense against invading organisms or irritants or things like that. And usually inflammation's really good at dealing with these organisms and getting rid of them and making us better. But if it's not properly controlled and it keeps on going, chronic inflammatory disease can result.

Narrator: Pain is experienced when inflammation builds up. Strausbaugh found molecular evidence suggesting this pain then signals the brain to put the brakes on inflammatory response before it reaches a disease state.

Strausbaugh: And how it does that is, it inhibits the first white blood cells called neutrophils that go into the inflammatory lesion.

Narrator: For Science Today, I'm Larissa Branin.


C. What's Behind the Upward Trend in Maximum Human Life Span?

Narrator: This is Science Today. Since 1970, there's been a slow upward trend in the maximum, human life span. Demographer John Wilmoth of the University of California, Berkeley, recently published these findings and says this trend accelerated mostly due to medical improvements in the treatment of cardiovascular disease.

Wilmoth: And there are various interventions that have improved the chances of survival once somebody suffers a heart attack or a stroke or rehabilitation therapies and drug therapies that reduce the risk of a subsequent attack and help people to recover. But then there are also medical means of treating some of the risk factors of heart disease and stroke, such as hypertension and high cholesterol and these play a role as well.

Narrator: But whether the upward trend in life span continues depends on our ability to maintain the current pace of progress in improving survivorship at older ages.

Wilmoth: In other words, we need to still stay focused on what's going on at younger ages because that's where development occurs, that's where the body is gaining what it's going to have later in life.

Narrator: For Science Today, I'm Larissa Branin.


D. A Small Telescope with Big Implications

Narrator: This is Science Today. A robotic telescope system called ROTSE, which was the first to capture a gamma ray burst in action, is surprisingly inexpensive compared to the standards of modern science. James Wren of the Los Alamos National Laboratory says everything on this system was pulled together with off the shelf products.

Wren: The ROTSE system itself consists of four Cannon telephoto lenses, two hundred millimeter - just normal things you can put on your very own camera and attached to those are CCD cameras which are electronic cameras and they work just like a normal camera. All the computers we use are normal, store-bought desktop PCs.

Narrator: With such humble components, ROTSE has proved to be a valuable tool for astronomers. It has a wider field of vision than large telescopes and can take about a thousand images a night of different locations.

Wren: And this data is very useful to astronomers who are looking for objects that can change on time scales that are short, as opposed to large observatories which only look at a single region of sky sometimes once every few weeks.

Narrator: For Science Today, I'm Larissa Branin.


E. Is Alzheimer's Disease Intrinsic to Aging?

Narrator: This is Science Today. It's true that the older a person is, the higher the odds are for getting Alzheimer's Disease, but this debilitating illness is not inevitable. Bruce Reed, co-director of the University of California, Davis Alzheimer's Center, says although the disease is in fact common, normal aging is common as well.

Reed: There is a degree of memory loss that happens normally as people age and it's very different than Alzheimer's disease and it's not that everybody's destined to get it. And it's not that if people get old enough they can't remember anymore. So there really is a normal and healthy side to aging and then there's this disease process.

Narrator: In fact, Reed says it seems the incidence of Alzheimer's Disease peaks sometime around age eighty-five and begins to decline after that.

Reed: It actually seems to be linked to some genetic factors and that with certain genetic factors the peak incidence is earlier - probably in the seventies. And then if you get through that, the risk actually begins to decline, which suggests that it's a disease process that is not intrinsic to aging.

Narrator: For Science Today, I'm Larissa Branin.

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu