Program 622,
  March 28, 2000

 

A. How a Simple Adjustment May Save Thousands of Lives

Narrator: This is Science Today. A national, clinical trial has found thousands of lives may be saved by simply adjusting a mechanical ventilator that supplies air to patients suffering from Acute Respiratory Distress Syndrome, or ARDS. Dr. Michael Matthay of the University of California, San Francisco who led the ten-city study, says ARDS is a severe type of respiratory failure in which the lungs fill with fluid.

Matthay: There are probably about sixty to eighty thousand people a year dying from ARDS. And the number of breast cancer deaths each year is forty-three thousand, so it's a major health care problem.

Narrator: Matthay and his colleagues cut the mortality rate down by 22 percent after re-setting the mechanical ventilators and giving patients shorter, oxygen-rich puffs of air, rather than the larger volumes previously given.

Matthay: The savings should be remarkable because in addition to reducing mortality, the study showed that the duration of time the patient spends on the ventilator, on the breathing machine is reduced also.

Narrator: For Science Today, I'm Larissa Branin.

B. Pesticide-Protective Clothing for Farm Workers

Narrator: This is Science Today. Farm workers and even home gardeners may benefit from chemically treated clothing similar to anti-bacterial fabrics in the works for the healthcare industry. Gang Sun, a professor of textiles and fabrics at the University of California, Davis, says his lab is working on developing cotton/polyester fabrics treated with a chemical that can detoxify pesticides on contact. The chemistry is based on the safe disinfectant compounds used in swimming pools.

Sun: Because we realized that the disinfectants not only kills the germs, it also decomposes some toxic chemicals.

Narrator: In initial testing Sun and his colleagues found fabrics treated with this compound almost instantly broke down two toxic agricultural pesticides into small, harmless fragments.

Sun: We are still studying what would be the fragments after the decomposition on the fabric because we want to prove all the fragments should be a safe chemical than the original pesticides. We're still doing the research on it.

Narrator: For Science Today, I'm Larissa Branin.

C. Managed Care Plans and Preventive Services

Narrator: This is Science Today. A health care watchdog organization recently found that although nearly half the nation's premature deaths were linked to such preventable causes as unhealthy diet, lack of exercise or substance abuse, few managed care plans routinely offer services to change these behaviors. Kathryn Phillips, a health services researcher at the University of California, San Francisco, says managed care plans historically haven't offered these services..

Phillips:Often because they don't see the results - the members changed plans before the plan can reap the benefits of a behavior change and it's sometimes much more difficult to provide that type of in-depth preventive service than it is to provide a simple screening procedure.

Narrator: Phillips cautions against thinking of managed care as one monolithic type of health plan.

Phillips: These days, most plans have some type of managed care feature, so we need to learn to think more specifically about what the characteristics of specific plans are.

Narrator: For Science Today, I'm Larissa Branin. .

D. A New Way to Measure Evasive, Small Pollution Particles

Narrator:This is Science Today. Small pollution particles that come from auto exhaust, power plants and a certain amount of photochemical smog, penetrate deeply into people's lungs. The more particles there are, the more people die and are admitted to hospitals for respiratory problems. Understanding just how these particles affect our health has proven difficult, because it's hard to get good measurements of these chemicals between the gas and airborne particle phase. Lara Gundel, a staff scientist at the Lawrence Berkeley National Laboratory, has come up with an air sampler to do just that.

Gundel: We devised a way to accurately separate the gases and the particles by basically trapping out the gases first and then catching the particles and then measuring the particles.

Narrator:This is done using what's called a diffusion denuder.

Gundel: Denude just means to remove, or to strip. The reason it's called a diffusion denuder is because it separates the gases and particles based on their different diffusion properties and speeds. The gases will go really fast like toddlers and the particles will go along with the flow - like a log in a river stream.

Narrator: For Science Today, I'm Larissa Branin.

E. How Doctors Can Better Control Pain

Narrator: This is Science Today. There are over two million deaths a year in the United States and more than half of these deaths occurs in hospitals. Steve Pantilat, a hospitalist at the University of California, San Francisco, says up to forty percent of people, regardless of the illness they had at the time of death, suffered moderate to severe pain.

Pantilat: These are people who are hospitalized. They're being cared for in an intensive care unit, so they had plenty of access to medical care and yet, they had moderate to severe pain at the end of life.

Narrator: A previous study found one of the reasons for this was the doctors' inability to adequately assess pain. In his own research, Pantilat, found doctors who simply believed their patients were in pain, were better at controlling it.

Pantilat: What I say to doctors when I teach about this is believe the patient. We have no way to measure whether someone is in pain. There's no machine. There's no blood test to tell whether or not a person is in pain. And in particular, people who have chronic pain, those people don't even look like they're in pain. And yet, what we know is that we're not very good at telling and we have to believe the patient..

Narrator: For Science Today, I'm Larissa Branin.

 

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu