Program 603,
  November 16, 1999

 

A. A Surprising Link Between Income and Nutrition
B. A Computerized Brain Cognition Test
C. What Doesn't Destroy You, Makes You Strong
D. Unlocking Pain Reduction Receptors in the Brain
E. Genetically Engineering the Environment

A. A Surprising Link Between Income and Nutrition

Narrator: This is Science Today. A common finding in most nutrition studies is those with lower incomes are not as properly nourished as those with higher incomes. But Joanne Ikeda, a nutritionist at the University of California, Berkeley found different results in her study on the diets of three generations of African-American women.

Ikeda: People at very low income levels have poorer diet quality, just because they don't have enough money to buy an adequate diet. In this study, that held true for the grandmothers and for the daughters. But it did not show true for the middle generation - that is, the mothers. It turned out that the higher income mothers actually had the poorer diets.

Narrator: One reason may be these working moms lack the time to cook and may just grab what they can outside the home.

Ikeda: As a matter of fact, one of their biggest sources of calories is french fries. So there probably is a lot of eating at fast food restaurants.

Narrator: For Science Today, I'm Larissa Branin.

B. A Computerized Brain Cognition Test

Narrator: This is Science Today. Computers can be used for almost everything these days. Now, they can even measure brain cognition. Dr. Louis Gottschalk, a neuroscientist at the University of California, Irvine, developed a computer program to help detect hostility, anxiety - even brain disorders. All a person has to do is talk into the computer for about five minutes.

Gottschalk: We've done studies of people coming to a psychiatric outpatient clinic and got speech samples and other measures and the five minute speech samples, it gives scores on some fifteen different psychological states and they tend to agree pretty well with what the clinician finds out.

Narrator: The computer program is based on the Gottschalk-Gleser scale, an international diagnostic tool used to measure cognitive impairment.

Gottschalk: It's capable of summarizing mathematically each score. So people send us material. Sometimes on a patient. There's some doctors that get this, get a five-minute speech sample and send me and use it as they might a psychological test.

Narrator: For Science Today, I'm Larissa Branin.

C. What Doesn't Destroy You, Makes You Strong

Narrator: This is Science Today. If the famous Nietzsche quote - What does not destroy me, makes me strong - rings true to you, chances are you're what Dr. Salvatore Maddi, a psychologist at the University of California, Irvine calls a hardy person. Maddi helps people deal with stress by teaching them what he calls hardiness skills.

Maddi: A lot of people tell us - well, hardiness - you either have it or you don't. It's in the genes. But you know, that's not really so true. If that was true, hardiness training wouldn't work the way it does and the research is very clear that it works.

Narrator: Hardiness training teaches people the coping and social support skills it takes to deal with stress.

Maddi: Hardy people believe whatever doesn't kill me makes me stronger. Our approach comes very much out of that kind of Nietzschian thinking. But what we feel is when a terrible circumstance overcomes you, you only have two options - give up or learn from it. And do something better. And some people actually do that.

Narrator: For Science Today, I'm Larissa Branin.

D. Unlocking Pain Reduction Receptors in the Brain

Narrator: This is Science Today. In the past decade, scientists have discovered two receptors in the brain which are affected by synthetic drugs called cannibinoids. These drugs mimic the active ingredient found in marijuana. Ian Meng, a researcher at the University of California, San Francisco, likens the relationship between these brain receptors and cannibinoids, to a lock and key.

Meng: The receptors are on the cell membrane and they're sort of like the lock and the cannibinoid, or the synthetic drugs we now have in the laboratory, can fit into that lock like they key and unleash all of its actions.

Narrator: Meng discovered these actions include a process similar to the release of natural endorphins which results in pain reduction.

Meng: And what we have now found is that the cannabinoids do the same thing. They can tap into this same brain circuitry and activate a very specific population of neurons to reduce the pain signal - just like the natural endorphins do.

Narrator: For Science Today, I'm Larissa Branin.

E. Genetically Engineering the Environment

Narrator: This is Science Today. Biochemical engineers at the University of California, Irvine are working to clean up contaminated sites by genetically engineering bacteria to degrade toxic compounds. Dr. Thomas Wood's laboratory at UC Irvine, is focusing on the bacteria near plant roots.

Wood: We're trying to encourage the bacteria to degrade trichloroethylene into carbon dioxide, which is chloride ions by giving these bacteria an additional gene that allows them to degrade this compound.

Narrator: And with trichloroethylene, a faster process is crucial since slow degradation results in a compound which is even more toxic.

Wood: What we're trying to do is prevent the trichloroethylene - the pollutant - from getting into the groundwater. Now, over the world, there are wells that have been contaminated and decommissioned because they have trichloroethylene and there are estimates that if you drink over your lifetime one part per million of trichloroethylene, about thirty-two people out of every hundred thousand would get cancer. So it's not something you want to drink routinely.

Narrator: For Science Today, I'm Larissa Branin.

Science Today is produced by the University of California
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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu