Program 598,
  October 12, 1999

 

A. Who Benefits The Most From Cholesterol Guidelines?
B. Should All Unruptured Aneurysms Be Treated?
C. How Doctors Can Help Victims Of Domestic Violence
D. The Growing Ethical Issues In Organ Transplantation
E. A New Device Detects An Insidious Poison

A. Who Benefits The Most From Cholesterol Guidelines?

Narrator: This is Science Today. A new study has found people with heart disease benefit more from current cholesterol guidelines than those without heart disease. Dr. Lee Goldman, a professor of medicine at the University of California, San Francisco says that's because those with existing heart disease are at higher risk and the cholesterol guidelines are more aggressive for them than the rest of the population.

Goldman: The first thing the study will do is get the guideline writers upset because they will fear that as a result, people without heart disease will not follow the guidelines and doctors will not pay attention to the guidelines.

Narrator: But Goldman says that's not the intent of the paper.

Goldman: What it really says is that in terms of keeping people alive, adding years of life or even quality years of life, that the principle focus should be on people that already have evidence of heart disease or who are at very, very high risk for it. Our paper really emphasizes that in secondary prevention, you not only get the most bang for the buck - you get the most bang.

Narrator: For Science Today, I'm Larissa Branin.

B. Should All Unruptured Aneurysms Be Treated?

Narrator: This is Science Today. For years, doctors have debated the value of surgically treating all unruptured cerebral aneurysms. While most do require surgical treatment, a new University of California, San Francisco study suggests that in a large subset of patients, such treatment is unnecessary. Dr. Clay Johnston, an assistant professor of neurology was lead author of the study.

Johnston: Previously, people, the numbers they had found were around one - one of those hundred would have a rupture in one year. And clearly at those levels, treatment was justified. But the new study's much larger than the previous ones, had found that in sub groups of patients, in ones with very small aneurysms where they hadn't had a ruptured aneurysm elsewhere, that their rupture rates were very, very low - in fact, one twentieth of one percent a year.

Narrator: This new information is reassuring to patients who had formerly thought of unruptured aneurysms as time bombs.

Johnston: They don't have a time bomb and they can go on and live their life normally and not necessarily expect to have any problems whatsoever from the aneurysm.

Narrator: For Science Today, I'm Larissa Branin.

C. How Doctors Can Help Victims Of Domestic Violence

Narrator: This is Science Today. Doctors can play a major role when it comes to helping patients who are victims of domestic violence. A new study has revealed physicians who simply acknowledged physical abuse had occurred and confirmed their patient's worth, had a very positive impact on these patients in the long run. Barbara Gerbert, a behavioral scientist at the University of California, San Francisco, interviewed women who had positive encounters with their doctors about their abuse.

Gerbert: We had thought we might find ephipanies. That is, a woman would say this happened with my physician and I immediately knew that I was in a dangerous situation and immediately took steps to leave.

Narrator: Instead, Gerbert found women described positive encounters with their doctor as 'planting the seeds of change' and even found many women clung to their doctor's validation.

Gerbert: Physicians may never see the outcomes of those efforts because they may never see the person again and yet, these women are out there and they have physicians to thank for their safety today.

Narrator: For Science Today, I'm Larissa Branin.

D. The Growing Ethical Issues In Organ Transplantation

Narrator: This is Science Today. Many difficult ethical issues have come up in the field of organ transplantation. Dr. John Roberts, chief of transplant services at the University of California, San Francisco, says because of a lack of donors, one of the main issues is deciding how to allocate organs.

Roberts: As the demand for transplantation increases, we're really left with these issues about how do we get organs distributed fairly or with justice?

Narrator: With limited resources, a philosophy called triage often comes into play.

Roberts: There's sort of wartime triage and there's peacetime triage. Peacetime triage generally occurs in situations where you have enough of a resource, you just have to figure out who needs to go first. Where, wartime triage is you just say, I can't take care of this guy - let him die. That's sort of the battlefield triage kind of system and one that transplantation, particularly of the life-saving organs, heart and liver is sort of been moving toward.

Narrator: For Science Today, I'm Larissa Branin.

E. A New Device Detects An Insidious Poison

Narrator: This is Science Today. Carbon monoxide poisoning is particularly insidious because it's odorless and in small doses, the symptoms resulting from exposure are very similar to other, non life-threatening ailments. Michael Apte, a scientist at the Lawrence Berkeley National Laboratory who has developed personal carbon monoxide sensors, says the symptoms often resemble the flu.

Apte: Dizziness, nausea, disorientation, headache…so unfortunately, when we're exposed at that level, if we go to the doctor, we're often misdiagnosed as having the flu. It can be a vicious cycle where people are continually exposed for many, many, many days - entire seasons sometimes.

Narrator: Apte's personal sensor can be used in the residential setting, but for now, Apte sees it more as an occupational research tool.

Apte: Public health departments, the state or federal environmental protection agencies, scientists who are interested in public health issues. They could use the device to measure carbon monoxide exposures within the workplace.

Narrator: For Science Today, I'm Larissa Branin.

Science Today is produced by the University of California
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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu