Program 552,
  November 24, 1998

 

A. The Biology Behind Drug Addiction
B. Lead Poisoning: A Silent Enemy
C. Estrogen's Effects On The Brain
D. Increasing The Range Of Laser Surgery
E. What Couples Should Know About Fertility


A. The Biology Behind Drug Addiction

Narrator: This is Science Today. Evidence that drug addiction has a biological basis is being studied at the University of California, San Francisco. Dr. Robert Malenka, a professor of psychiatry, says drug addiction is now viewed by many scientists as a biological brain disorder, similar to depression.

Malenka: Obviously, it's not just biology. There's incredibly important environmental influences, individual psychological differences that contribute to whether somebody becomes addicted or not, I mean those influences are clearly incredibly important.

Narrator: But Malenka says so are biological influences. Clinical studies have found drugs of abuse can activate neural circuits in the brain responsible for a natural reward process.

Malenka: A natural reward is associated with feelings of warmth - filling up your stomach when you eat food. The thought is that a drug of abuse sort of goes in there, interacts with these neural circuits and activates them, but in an unnatural way.

Narrator: Chronic intake of drugs seems to alter the natural reward process permanently. For Science Today, I'm Larissa Branin.


B. Lead Poisoning: A Silent Enemy

Narrator: This is Science Today. Although Congress banned the use of lead paint back in 1971, there are still about 57 million homes in the country which are contaminated with lead based paints. But Los Alamos National Laboratory researcher, Chuck Wilkerson says paint flakes are not the only way children get lead in their system.

Wilkerson: Certainly having the lead flakes is a higher source in terms of concentration of lead, but it's not the only one they're exposed to as constantly. With the reduction of the amount of use of lead in fuels, lead in the environment has decreased a lot, but there's still so many places industrially, that lead is used.

Narrator: Once in the atmosphere, this lead is deposited in the soil and inhaled, which can lead to a variety of very serious physical and mental problems.

Wilkerson: It has been shown to decrease the IQ of developing children. It's been shown to cause behavioral problems. It's been shown to affect neuro-muscular development. It's been shown to affect blood production. And so it's a very, very serious problem.

Narrator: For Science Today, I'm Larissa Branin.


C. Estrogen's Effects On The Brain

Narrator: This is Science Today. The hormone estrogen has recently been suggested to have an effect on Alzheimer's Disease. Dr. Gary Small, director of UCLA's Center on Aging and a professor of psychiatry says estrogen seems to increase memory in patients who already have Alzheimer's.

Small: In addition to that, there are epidemiological observational studies where it seems that women who take estrogen have a lower risk for developing Alzheimer's Disease.

Narrator: UCLA is currently involved in a multi-site study on estrogen's effects on the brain, including it's seeming role as an anti-depressant.

Small: I think it's an exciting time to be looking at estrogen effects on the brain. There's greater recognition of some of the mental problems affecting women as they age and certainly depression and cognitive impairment are the major problems that older women face and estrogen may help them deal with some of these problems.

Narrator: For Science Today, I'm Larissa Branin.


D. Increasing The Range Of Laser Surgery

Narrator: This is Science Today. You may have heard about those new laser dental drills, which actually cut through hard tissue more efficiently and less painfully. Well, UCLA School of Dentistry professor Roy Eversole says these new types of laser systems don't have to be limited to just teeth.

Eversole: It is very, very effective in cutting bone. We see that these systems have wide applicability in plastic surgery, orthopedic surgery, podiatric surgery with a system that is number one, basically bloodless. It doesn't char. It doesn't burn, it doesn't heat up the tissue. It's very, very clean.

Narrator: Eversole says as a surgical device, using laser technology with hard tissue is minimally invasive and would probably minimize complications in wound healing.

Eversole: I think this new system, although it's first developed for dentistry, will become a very important surgical tool for really precise, little micro-surgical things in the medical fields.

Narrator: For Science Today, I'm Larissa Branin.


E. What Couples Should Know About Fertility

Narrator: This is Science Today. About 15 percent of American couples have trouble conceiving a child. According to male fertility specialist Paul Turek of the University of California, San Francisco, about 40 percent of the problem is male related and since it's sometimes easily correctable, Turek says it's important for a man to see a specialist.

Turek: It's just as important that the man go see someone who knows a lot about him as the woman goes to see someone who knows a lot about her. Now women tend to be more proactive about it, take care of themselves better medically. Men sort of have a cultural problem because they have to work hard and have to make money and they can't be weak or ill because then things will fall apart, supposedly.

Narrator: But Turek says about one out of five men don't know the proper techniques of conceiving a child, so simple counseling can greatly help.

Turek: What kinds of lubricants do you use, avoiding hot tubs, all things in moderation. Keeping healthy overall, exercising, you know eating a good diet makes good reproductive sense, too. A healthy body is a healthy reproductive body.

Narrator: For Science Today, I'm Larissa Branin.

 

 

 

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For comments or more information about Science Today, contact Larissa Branin at larissa.branin@ucop.edu