Program 506,
  January 6, 1998

 

A. The Best Practice for Heart Patients
B. The Laboratory of the Future
C. Becoming Aware of Glaucoma
D. One of the Underrated Senses
E. The Future of Cartilage Tissue Engineering


A.The Best Practice for Heart Patients

Narrator: This is Science Today. Heart patients do better at medical centers which follow the federal Abest practice@ guidelines for congestive heart failure. Pat Sparacino, a clinical nurse specialist at the University of California, San Francisco says these guidelines were developed by the Agency for Health Care Policy and Research.

Sparacino: These guidelines are recommendations about symptom recognition, symptom management and the incorporation of exercise, importance of taking drugs, the importance of low salt containing foods to basically be able to best manage their congestive heart failure.

Narrator: By following these guidelines, hospital readmission rates dropped and there was also a decrease in cost and the patient's length of stay.

Sparacino: It also gives them some ownership of their disease management. It becomes a true partnership, that it isn't just the care providers, it's the care provider and the patient and hopefully patient's family.

Narrator: For Science Today, I'm Larissa Branin.


B. The Laboratory of the Future

Narrator: This is Science Today. A hand held device may be the laboratory of the future. Michael Sailor, a chemistry professor at the University of California, San Diego says rather than having patients undergo a barrage of expensive tests, a bio sensor device could diagnose several deficiencies and diseases right away. This can be done by packing certain biological molecules onto a silicon wafer.

Sailor: You've got something sitting on the surface of this thing that's tuned to recognize this specific molecule. Let's say you have the AIDS antibody, we have something on that surface that can recognize the AIDS antibody. We take your blood sample and put it into there and if you've got AIDS, the color changes.

Narrator: Sailor says this silicon wafer is similar to a pentium processor chip.

Sailor: And so what we want to do is be able to sculpt maybe ten thousand or a hundred thousand little analytical patches on the silicon, feed the sample of saliva or the blood sample to the chip and have it do the thousand or ten thousand different analyses you want it to do and tell you what are all the problems with this particular sample.

Narrator: For Science Today, I'm Larissa Branin.


C. Becoming Aware of Glaucoma

Narrator: This is Science Today. January is glaucoma awareness month and therefore, a good time for those at risk to have an annual eye exam. Dr. Robert Weinreb of the University of California, San Diego says those at greatest risk are the elderly.

Weinreb: After the age of seventy, for example, there is a risk of more than five percent that you might develop glaucoma. Other individuals who are at risk are those with high eye pressure. African Americans have about a four fold greater risk of developing glaucoma and about an eight fold risk of going blind from glaucoma.

Narrator: Glaucoma is a condition in which the optic nerve is damaged.

Weinreb: And the damage leads to loss of vision and possible blindness. In the earliest stages of glaucoma, there's no obvious loss of vision to the patient and glaucoma can only be detected with specialized testing of vision.

Narrator: For Science Today, I'm Larissa Branin.


D. One of the Underrated Senses

Narrator: This is Science Today. If you lost your sense of smell, would you notice it? Surprisingly, Dr. Terence Davidson, an ear, nose and throat specialist at the University of California, San Diego says many times, people don't.

Davidson: It's not so well defined and it's not well picked up and it's not so obvious. So it takes them a while to figure it out, then they're not sure whether to make a big deal of it.

Narrator: Davidson says it's usually people who depend more on their noses who come in for treatment.

Davidson: The classic example is a housewife. She knows when the baby's diapers are full, she goes around picking up articles of clothing, giving them a sniff to see if it goes back into the drawer or whether it goes into the laundry. She cooks by her nose, she cleans by her nose. They'll come in day one when they lost their sense of smell. I assume a chef would know immediately. Wine tasters would know the moment the first neuron went.

Narrator: Most of the time, the loss of smell is caused by inflammatory nasal disease, which Davidson says is reversible. For Science Today, I'm Larissa Branin.


E. The Future of Cartilage Tissue Engineering

Narrator: This is Science Today. While the concept of tissue engineering of knee cartilage has been making waves in the press lately, bioengineer Robert Sah of the University of California, San Diego, says it's too soon for people to get their hopes high.

Sah: Older people who have completely degenerate joints think that there's a cure in the near horizon for their totally degenerate joints and that's not the case. I think we're fifty to one hundred years away from that.

Narrator: Sah helped create a detailed, mechanical blueprint of the knee cartilage which may be valuable in engineering better matched, laboratory grown knee cartilage.

Sah: The really wonderful thing that might happen many, many years down the line, which some people have a vision for, is that we'll develop a totally synthetic, living cartilage, bone replacement that will replace the metal and plastic prosthesis we put into older people and will overcome some of the limitations.

Narrator: For Science Today, I'm Larissa Branin.

 

 

 

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