Program 466,
  April 1, 1997

 

A. The Harmful Side of Something Good
B. The Best Kept Secret
C. Helping AIDS Patients End Their Lives
D. A Doctor's Guide to Protease Inhibitors
E. Smoke-Free by the year 2000?


A. The Harmful Side of Something Good

Narrator: This is Science Today. It's a good idea to take antioxidants to prevent cancer, right? Not necessarily, says Dr. Courtney Broaddus of the University of California, San Francisco. In the lab, she found that giving high doses of antioxidants to lung cells helps the cells survive -- but they develop strange mutations and may get cancer later on.

Broaddus: What everyone would have thought made perfect sense turned out to reveal an unexpected and harmful side of something that seemed so good for us.

Narrator: Her work supports the findings of other researchers, who say that the thing to do is not take lots of high-dose antioxidant pills...

Broaddus: ...but rely on the tried and true source of antioxidants, which are vegetables and fruits. Because they contain either the right combination of antioxidants or the right concentrations of fiber together with antioxidants, whatever combination they have, they are the beneficial entity -- and not something that we purify from them and think that we've got the answer.

Narrator: For Science Today, I'm Steve Tokar.


B. The Best Kept Secret

Delbanco: Emergency contraception is referred to as the best kept secret.

Narrator: This is Science Today. There's a birth control method that's effective and safe that many people don't know about, according to public health expert Suzanne Delbanco of the University of California, Berkeley. It's called "emergency contraception."

Delbanco: Most of the time today when you hear that term, people are referring to the use of high-dose oral contraceptives used after unprotected intercourse to prevent pregnancy.

Narrator: Another name for it is the "morning after pill." Surprisingly, obstetricians and gynecologists know about it but don't talk about it.

Delbanco: Although they're all incredibly familiar with this as a method, and they wholly endorse it as far as its safety and effectiveness goes, they rarely tell their patients.

Narrator: Delbanco says that women who know about it tend to be graduates of four-year universities, where the idea is promoted to students.

Delbanco: And women who are older tend to know about it, I think mostly because they've been around longer and have had a greater chance to hear about this as a contraceptive alternative. So what we see is the need for the public to be informed about it so they can demand this as a service when they need it.

Narrator: For Science Today, I'm Steve Tokar.


C. Helping AIDS Patients End Their Lives

Narrator: This is Science Today. As the national debate over physician-assisted suicide continues, a study of doctors who treat AIDS patients found that over half the doctors admitted to helping some patients end their lives. Dr. Donald Abrams of the University of California, San Francisco says the usual method was to prescribe lethal doses of painkillers or barbiturates.

Abrams: That is, written prescriptions so that patients have access to these medications when they decide that they would like to leave this world.

Narrator: But Abrams notes the survey was conducted before the powerful AIDS drugs known as protease inhibitors became available.

Abrams: And certainly, currently we're in a new era of enthusiasm and hope for treatment, for possibly eradicating the virus from individuals, some people even mention the word cure. I think it would be interesting to again repeat this questionnaire in another five years if we're still dealing with AIDS as we know it today, and see what the situation is.

Narrator: For Science Today, I'm Steve Tokar.


D. A Doctor's Guide to Protease Inhibitors

Narrator: This is Science Today. Protease inhibitors, powerful new AIDS drugs, are raising new hopes that the virus might be defeated, or at least contained. But the drugs are so new, doctors often aren't sure when or how to prescribe them. Dr. James Kahn of the University of California, San Francisco hopes to change that with a new study -- a sort of doctor's guide to protease inhibitors.

Kahn: Effective treatments are on the market even before studies that led to their approval have been peer-reviewed. So we thought that the regular providers who see patients were going to be left to the kinds of information that the pharmaceutical companies would like them to receive. And that's certainly not a fair or unbiased approach.

Narrator: It's unusual for drugs to be released before they're studied. But AIDS isn't your usual epidemic, says Kahn.

Kahn: You don't know if you're doing it the best way. You certainly know you're doing it an effective way. So I think a lot of the refinements will occur after the drugs have been marketed, but at least that way, patients have access to them.

Narrator: For Science Today, I'm Steve Tokar.


E. Smoke-Free By the Year 2000?

Narrator: This is Science Today. The author of The Cigarette Papers, a nationwide expose of the tobacco industry, says current anti-smoking campaigns aren't working. Dr. Stanton Glantz of the University of California, San Francisco says the main reason is the focus on getting kids to stop smoking.

Glantz: What we've seen once we got into this let's kids from smoking rhetoric is more kids are smoking. And so I'm very worried that by shifting away from a general message of a smoke-free society to let's keep kids from smoking, that's another very damaging thing.

Narrator: Instead, Glantz says regulatory agencies should pursue a just-don't-smoke campaign.

Glantz: I think that this complete preoccupation with kids is doomed to fail, and if the health groups figure out that that's a mistake and get back to the general message of a smoke-free society, they can recover from it.

Narrator: If that happens, Glantz says the idea of a smoke-free country by the year 2000 is not so far-fetched. For Science Today, I'm Steve Tokar.

 

 

 

 

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