Narrator: This is Science Today. In yet another instance of technology driving science, researchers at the University of California, San Francisco were able to discover for the first time that a leukemia cell can change the microenvironment of the bone marrow niche, to the point where healthy stem cells are kicked out of a hostile environment. Dr. Emmanuelle Passegue who led this study, says for a long time it was impossible to follow just what was happening within the bone without destroying the niche.
Passegue: So, until recently where we started really being able to section and image high resolution visualization of this hematopoietic stem cell with the bone marrow cavity, we knew almost nothing about the niche. So, the niche is really a new frontier of understanding the biology of this organ because we are starting to get the tool to really get inside the bone and start to see what's happening.
Narrator: Passegue adds that their work is merely scratching the surface of what's coming up in terms of understanding the normal biology of the niche. For Science Today, I'm Larissa Branin.