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Challenges of moving discoveries from lab to clinic


Narrator:       This is Science Today. One of the primary goals of a translational research center at the University of California, San Francisco-affiliated Gladstone Institutes is to turn basic science into therapeutics that can help patients with cardiovascular, viral or neurological diseases. Clinical neurologist Dr. Steve Finkbeiner explains that one of the most challenging steps in research is moving discoveries from the lab to the clinic.

Finkbeiner:   There are really good structures to support basic research and there are drug companies that develop drugs, but there's this big chasm in the middle, which is where our basic research ends off and where it actually has be before a drug company says that looks promising enough to pursue and to make their investment.

Narrator:       Finkbeiner says local philanthropists have been ideal partners by helping the center do additional research to move it far enough down the line. 

Finkbeiner:   So that we can say to drug companies this really does look promising, you should take a look and see if we can work together to see if we can develop these things.

Narrator:       For Science Today, I'm Larissa Branin.