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A. An Anti-Fungal Drug May Help Treat Cancer

Narrator: This is Science Today. A drug that's been used for more than four decades to treat fungal infections of the skin, such as ringworm, may help treat cancer. Biochemist Leslie Wilson of the University of California, Santa Barbara says the anti-fungal drug, griseofulvin, was found to inhibit the spread of cancer cells by affecting cell division. It works in a way that's similar to much more potent anticancer drugs such as Taxol, but without the toxicity.

Wilson: So, the lack of toxicity with a similar mechanism, but lower potency, gave us the thought that this drug, together with more powerful drugs used for cancer, the drug could be an adjuvant in cancer treatment therapy.

Narrator: Wilson says since griseofulvin concentrates in the skin as an anti-fungal agent, it could potentially be used as an adjuvant to help treat skin cancer.

Wilson: The advantage of using a drug like this is it's already approved, it's been used a very, very long time and it's relatively safe and non-toxic. So, it's relatively straightforward to initiate such a trail.

Narrator: For Science Today, I'm Larissa Branin.