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E. Evidence of a Molecular Link Between Inflammation & Cancer

Narrator: This is Science Today. A positive link between cancer and inflammation has long been suggested, but researchers at the University of California, San Diego School of Medicine discovered the first evidence of a direct molecular link between inflammation and cancer. Michael Karin, a professor of pharmacology, notes that in their study, acute inflammation resulted in the production of two different kinds of substances.

Karin: Both of which are cytokines, which are sort of hormones that are produced in response to infection or inflammation and so on. And one cytokine was responsible for stimulation of the growth of the tumors and another one had the potential to kill the tumor and they were both produced at the same time.

Narrator: The ultimate goal is to develop new drugs that can block tumor growth proteins and stimulate the cancer killing ones.

Karin: There's still a lot of things which we don't understand, but I think now the pace of getting new knowledge is really accelerated.

Narrator: For Science Today, I'm Larissa Branin.