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A. A Class of Drugs that's Effective Against Atherosclerosis

Narrator: This is Science Today. A class of drugs used to reduce cholesterol levels and inhibit the development of diabetes, is also effective in the prevention of the fatty plaques that cause atherosclerosis. Dr. Christopher Glass of the University of California, San Diego School of Medicine discovered that drugs, which activate two types of proteins known as PPAR-gamma and PPAR-alpha, can prevent atherosclerotic lesions in artery walls by up to 70 percent.

Glass: Here's a drug where it will impact on the primary problem, diabetes, but also have a beneficial impact on a complication of diabetes by acting directly on the artery wall to slow down the pathological processes the drive this disease. So I think this will probably influence how doctors use these drugs down the line. Now our work is all in animals, so this is a major impetus to try and translate the work that we've done in animals into clinical trials involving patients, but this is very transferable.

Narrator: For Science Today, I'm Larissa Branin.