Hamilton: What this highlights is that we know very little about how antidepressants work - what they do in the brain. We know that they work and we know there's a period of time that's usually required for them to work, but we are only now beginning to get a glimpse of the biological processes that are underlying people getting better on these drugs.
Narrator: Hamilton's work so far suggests that genes they had not previously known about may actually be involved.
Hamilton: If we're able to identify more specific targets for these drugs through genetic analysis that may give us a leg up in coming up with better treatments that make people feel better faster and with much more reliability.
Narrator: For Science Today, I'm Larissa Branin.